Results 51 to 60 of about 24,513 (247)

Antigen‐Detected NMR for Minimal Epitope Engineering and Structure‐Guided Selection of a NaV1.7‐Selective Nanobody

Advanced Science, EarlyView.
A minimal extracellular epitope from voltage‐gated sodium channel NaV1.7 was engineered into an isotope‐labelled antigen for antigen‐detected nuclear magnetic resonance (NMR). Together with AlphaFold2 (AF2), this enabled structure‐guided selection of R4C8, a human NaV1.7‐selective nanobody that labels fixed NaV1.7‐expressing cells and produces staining
Junyu Liu, Wanlin Chen, Ben Cristofori‐Armstrong, Theo Crawford, Kai‐En Chen, Peng Xie, Rainbow Wing Bo Chan, Yifei Zhu, Mimi Golder, Anneka Pereira Schmidt, Jennifer D. Naughton, Nicholas D. Condon, Åsa Andersson, Farhad Dehkhoda, Kirsten L. McMahon, Tabea Klasfauseweh, Ashvriya Thapa, Hue Tran, Poanna Tran, Sina Jami, Lotten Ragnarsson, Sebastian G. B. Furness, Jennifer R. Deuis, Brett M. Collins, Wai‐Hong Tham, Indira Prasadam, Irina Vetter, Mehdi Mobli   +27 more
wiley   +1 more source

Examining the Volatility of Oil Revenue and its Impact on Algeria’s Macroeconomic Stability

Folia Oeconomica Stetinensia
Algeria heavily relies on its oil revenues, being one of the leading crude oil producers in Africa and a key member of OPEC. This dependency exposes its economy to the volatility of oil prices in international markets, which can have significant ...
Bouyacoub Brahim
doaj   +1 more source

World capital markets facing the first wave of COVID-19: Traditional event study versus sensitivity to new cases

Economics and Business Review, 2022
The aim of the paper is to analyse the impact of the new coronavirus on financial markets. The sample comprises returns from 80 countries, across all regions and incomes for the period known as the first wave.
Angosto-Fernández Pedro Luis, Ferrández-Serrano Victoria   +1 more
doaj   +1 more source

C32 nanoparticle delivery of pSP-D-CD40L slowed tumor growth and prolonged survival.

, 2013
The data shown are representative of three independent experiments. Panel A – Antitumor effects of C32 nanoparticles prepared with pSP-D-CD40L plasmid vs. control pcDNA3.1 plasmid either alone or in combination with CpG or CpG + poly(I:C).
Suzanne Barzee (370076), Daniel G. Anderson (166832), Richard S. Kornbluth (370079), Gregory T. Zugates (370078), Robert Langer (166824), Camila Santucci (142715), Geoffrey W. Stone (370075), Brian Tran (370077), Victoria Snarsky (332745)   +8 more
core   +1 more source

A Unifying Approach to Self‐Organizing Systems Interacting via Conservation Laws

Advanced Intelligent Discovery, EarlyView.
The article develops a unified way to model and analyze self‐organizing systems whose interactions are constrained by conservation laws. It represents physical/biological/engineered networks as graphs and builds projection operators (from incidence/cycle structure) that enforce those constraints and decompose network variables into constrained versus ...
F. Barrows, G. Zhang, S. Anand, Z. Chen, J. Lin, A. Desai, S. Martiniani, F. Caravelli   +7 more
wiley   +1 more source

Social and economic development of Ukraine: Modelling the migration factor impact

Economics and Business Review, 2022
The paper aims to analyse the dependence of the economic and social development of Ukraine on migration factors (human resources and remittances) in the years 2002–2020.
Vasyltsiv Taras, Mulska Olha, Osinska Oksana, Makhonyuk Oleksandr   +3 more
doaj   +1 more source

Pasado y presente de la disputa del psicologismo y el logicismo. Hacia el proyecto de una normatividad del entendimiento humano

, 2022
[ES]El estudio elabora una génesis del psicologismo y su relación con el logicismo en el contexto de la filosofía alemana del siglo XX. Se explora las distintas formas en las que el psicologismo se ha ido desarrando a los largo de los debates filosóficos
Hernández Marcelo, Jimmy
core  

Glutaredoxine reduzieren schnell Glutathionhydroper‐ und Glutathionpolysulfide

Angewandte Chemie, EarlyView.
Glutaredoxine (Grx) reduzieren Glutathionpolysulfide (GSSnSG) schnell zu Glutathionhydroper/polysulfiden (GSSnH) oder GSSnH zu Wasserstoff(poly)sulfiden (H2Sn). Die Reduktion glutathionylierter Grx durch reduziertes Glutathion (GSH) liefert Glutathiondisulfid (GSSG).
Philipp Reinert, Seiryo Ogata, Laura Leiskau, Sernur Sena Yildiz, Takaaki Akaike, Uladzimir Barayeu, Marcel Deponte   +6 more
wiley   +1 more source

Estimativa da ingestão e digestibilidade de erva e bolota em porcos alentejanos pela técnica dos n-alcanos Estimation of intake and digestibility of pasture and acorns by alentejano pigs using n-alkanes

Revista de Ciências Agrárias, 2007
Com o objectivo de estimar, em porcos Alentejanos, a ingestão e a digestibilidade de erva e bolota, foi realizado um ensaio utilizando n-alcanos de cadeia longa como marcadores fecais.
C. Mendes, M. I. Ferraz-de-Oliveira, T. Ribeiro, M. C. d’Abreu   +3 more
doaj  

Proline Dehydrogenase/Proline Oxidase (PRODH/POX) Is Involved in the Mechanism of Metformin-Induced Apoptosis in C32 Melanoma Cell Line

, 2022
The role of proline dehydrogenase/proline oxidase (PRODH/POX) in the mechanism of antineoplastic activity of metformin (MET) was studied in C32 melanoma cells.
Ilona Oscilowska, Magdalena Sawicka, Karol Rolkowski, Weronika Baszanowska, Sylwia Lewoniewska, Jerzy Palka, Katarzyna Bielawska, Thi Yen Ly Huynh, Wojciech Miltyk, Magdalena Nizioł, Paweł Szoka   +10 more
core   +1 more source