Results 101 to 110 of about 27,277 (237)

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Álcalis incorporados ao aluminato tricálcico: efeitos na hidratação

Ambiente Construído
O aluminato tricálcico (C3A) é a fase que reage mais rápido na hidratação do cimento quando em contato com a água. Geralmente, a forma cristalina sintetizada durante o processo de clinquerização é cúbica.
Ana Paula Kirchheim, Rui Barbosa de Souza, Denise Carpena Coitinho Dal Molin, Paulo José Melaragno Monteiro   +3 more
doaj   +1 more source

Implementation Punctuation: The Role of Feedback, Narratives, and Implementation in the Punctuated Equilibrium Theory

Policy Studies Journal, EarlyView.
ABSTRACT Based on the Punctuated Equilibrium Theory (PET) and implementation research, this study proposes an extended conceptualization of policy punctuation that enables researchers to systematically include policy implementation as part of a punctuation. The key mechanisms underlying the PET, i.e., policy image and venue, information processing, and
Bettina Stauffer
wiley   +1 more source

Assessing D‐Squame as a Minimally Invasive Technique to Evaluate the Cutaneous Immune Response mRNA in a Dog Model of Canine Atopic Dermatitis

Veterinary Dermatology, EarlyView.
ABSTRACT Background Canine atopic dermatitis (cAD) is a multifactorial, inherited skin disease, estimated to affect ≤ 15% of dogs. Studies of skin messenger mRNA in cAD currently use invasive methods, including blood sampling and biopsy collection, whilst advances in human atopic dermatitis study methodology have demonstrated reliable use of minimally ...
Xavier Langon, Marion Mosca, Nadège Milhau, Mélanie Legain, Adrien Idée, Didier Pin   +5 more
wiley   +1 more source

The specific contributions of factor H and factor I in controlling fluid phase activation of the alternative complement pathway

Scientific Reports
The immediate defense provided by the alternative complement pathway (AP) is under constant control by fluid phase regulators, factor H (FH) and factor I (FI), to prevent nonessential activation.
Nancy A. Turner, Joel L. Moake
doaj   +1 more source

Tolerability and Feasibility of Minimally Invasive Canine Skin Sampling: Excellent Tolerability Meets Transcriptomic Challenges

Veterinary Dermatology, EarlyView.
ABSTRACT Background Advances in transcriptomics have driven the demand for minimally invasive, reproducible and high‐yield skin sampling methods, particularly for studying inflammatory skin diseases in companion animals. Hypothesis/Objectives We tested tolerability, feasibility and RNA quantity and quality of three minimally invasive skin sampling ...
Ina Herrmann, Lisa B. Mamo, Allison N. Dickey   +2 more
wiley   +1 more source

Amplicon sequencing and culture-dependent approaches reveal core bacterial endophytes aiding freezing stress tolerance in alpine Rosaceae plants

mBio
Wild plants growing in alpine regions are associated with endophytic microbial communities that may support plant growth and survival under cold conditions.
Malek Marian, Livio Antonielli, Ilaria Pertot, Michele Perazzolli   +3 more
doaj   +1 more source

The complement C3a/C3aR pathway is associated with treatment resistance to gemcitabine-based neoadjuvant therapy in pancreatic cancer

Computational and Structural Biotechnology Journal
Gemcitabine is a standard first-line drug for pancreatic cancer chemotherapy. Nevertheless, gemcitabine resistance is common and significantly limits its therapeutic efficacy, impeding advancements in pancreatic cancer treatment. In this study, through a
Saimeng Shi, Longyun Ye, Kaizhou Jin, Xianjun Yu, Duancheng Guo, Weiding Wu   +5 more
doaj   +1 more source

Blood Serum From Obese Women Raises ROS Production by Neural Stem Cells

Developmental Neurobiology, Volume 86, Issue 2, April 2026.
ABSTRACT Maternal obesity has been associated with adverse pregnancy outcomes and altered fetal development, but the direct influence of circulating maternal factors on early human neural cells remains poorly understood. Neural stem cells (NSCs) provide a controlled system to examine how metabolic and inflammatory changes may affect early ...
Phelipe Elias da Silva, Natássia Caroline Resende Corrêa, Natália Ferreira Silva, Carlos Ueira‐Vieira, Hebreia Oliveira Almeida‐Souza, Mario Machado Martins, Tiara da Costa Silva, Renata Graciele Zanon   +7 more
wiley   +1 more source

Associations between serum complement component 3a and sC5b⁃9 levels with the prognosis of sepsis patients

Zhongguo linchuang yanjiu
"Objective To investigate the associations of serum complement component 3a（C3a）and soluble terminalcomplement complex C5b⁃9（sC5b⁃9）levels with the severity of sepsis and 28⁃day clinical prognosis among patients，and to provide new biomarker references ...
SU Yixing，BAO Lei，YU Jun'an，GU Zhijian
doaj   +1 more source