Results 121 to 130 of about 24,276 (249)

In Xenopus oocytes the human C3a and C5a receptors elicit a promiscuous response to the anaphylatoxins [PDF]

, 1996
The Xenopus laevis oocyte has been widely utilized for cloning and functional expression of G-protein coupled receptors (GPCR). This system was used for the functional expression and characterization of the recently identified human C3a receptor ...
Robert S Ames, Paru Nuthulaganti, Nuthulaganti, Paru, Chandrika Kumar, Kumar, Chandrika, Ames, Robert S   +5 more
core   +1 more source

In Situ X‐Ray Diffraction Study of a Microwave‐Based Hydrothermal Synthesis of Mayenite Ca12Al14O33

Zeitschrift für anorganische und allgemeine Chemie, EarlyView.
Microwave‐assisted hydrothermal synthesis enables rapid transformation of aluminium‐ and calcium‐hydroxide into mayenite with high surface area. Optimised synthesis conditions comprise a microwave step at 80°C for 5 min followed by calcination at 800°C. The reactions during calcination were studied via in situ XRD measurements.
Nils L. Kotschote, Franziska Hupe, Gina‐Lee Pitulle, Stefan G. Ebbinghaus   +3 more
wiley   +1 more source

The Complement System in Post‐Transplant Kidney Injury

Organ Medicine, EarlyView.
Mengsi Hu
wiley   +1 more source

Effect of molecular perturbation on cocrystal formation: theophylline and its 8‐halo analogues with flavonoids

Acta Crystallographica Section C, EarlyView.
The tendency for alkaloid–flavonoid cocrystal formation is found to be markedly different for theophylline (Tph) compared to its 8‐halo analogues. Through screening with 13 common flavonoids, Tph is found to form cocrystals with six flavonoids, whereas 8‐Cl‐Tph and 8‐Br‐Tph each form cocrystals with just two, myricetin and kaempferol.
Weijian Ye, Herman H-Y. Sung, Ian D. Williams   +2 more
wiley   +1 more source

IL‐33 Drives Inflammatory Changes and Extracellular Trap Formation in Eosinophils Involving Oxidised LDL and Complement Pathways

Allergy, EarlyView.
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama, Jun Miyata, Takao Mochimaru, Ryuta Onozato, Yo Otsu, Hisashi Sasaki, Keeya Sunata, Shinichi Okuzumi, Katsunori Masaki, Hiroki Kabata, Keinosuke Hizuka, Yoshinori Hasegawa, Ryo Konno, Yusuke Kawashima, Makoto Arita, Shigeharu Ueki, Koichi Fukunaga   +16 more
wiley   +1 more source

The specific contributions of factor H and factor I in controlling fluid phase activation of the alternative complement pathway

Scientific Reports
The immediate defense provided by the alternative complement pathway (AP) is under constant control by fluid phase regulators, factor H (FH) and factor I (FI), to prevent nonessential activation.
Nancy A. Turner, Joel L. Moake
doaj   +1 more source

Increase in prostanoid formation in rat liver macrophages (Kupffer cells) by human anaphylatoxin C3a [PDF]

, 2008
Human anaphylatoxin C3a increases glycogenolysis in perfused rat liver. This action is inhibited by prostanoid synthesis inhibitors and prostanoid antagonists.
Dieter, Peter, Püschel, Gerhard Paul, Oppermann, Martin, Hespeling, Ursula   +3 more
core  

Álcalis incorporados ao aluminato tricálcico: efeitos na hidratação

Ambiente Construído
O aluminato tricálcico (C3A) é a fase que reage mais rápido na hidratação do cimento quando em contato com a água. Geralmente, a forma cristalina sintetizada durante o processo de clinquerização é cúbica.
Ana Paula Kirchheim, Rui Barbosa de Souza, Denise Carpena Coitinho Dal Molin, Paulo José Melaragno Monteiro   +3 more
doaj   +1 more source

Basophils in Immunity: Activation Pathways, Roles in Allergy and AllergoOncology and Application of the Basophil Activation Test

Allergy, EarlyView.
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan, Sofia Vlasova, Alicia Chenoweth, Debra H. Josephs, Heather J. Bax, Sophia N. Karagiannis   +5 more
wiley   +1 more source

Acute anaphylactic and multiorgan inflammatory effects of Comirnaty in pigs: evidence of spike protein mRNA transfection and paralleling inflammatory cytokine upregulation

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Rare but severe adverse events (AEs) associated with mRNA‐lipid nanoparticle (LNP) COVID‐19 vaccines, such as Comirnaty, include anaphylaxis and inflammatory organ disorders, but their underlying mechanisms are poorly understood. We aimed to develop an animal model to study these phenomena.
László Dézsi, Gábor Kökény, Gábor Szénási, Csaba Révész, Tamás Mészáros, Bálint A. Barta, Réka Facsko, Anna Szilasi, Tamás Bakos, Gergely T. Kozma, Attila B. Dobos, Béla Merkely, Tamás Radovits, János Szebeni   +13 more
wiley   +1 more source