Results 141 to 150 of about 56,153 (264)
Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma
eFood, Volume 7, Issue 3, June 2026.Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie +5 more
wiley +1 more source
MicrobiologyOpen, Volume 15, Issue 3, June 2026.IMP‐1700 enhances the cytotoxic effect on bacteria in combination with either ciprofloxacin (CPX) or X‐ray. In noncancerous and tumor cells, combination treatments markedly reduce viability with radiosensitizing effects. Further studies are needed to clarify the mechanism underlying IMP‐1700s effects on mammalian cells. Created in BioRender. Kjaer, A. (
Ida Vang Andersen +7 more
wiley +1 more source
Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases
MedComm, Volume 7, Issue 6, June 2026.Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu +9 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 11, Page 2874-2889, June 2026.Abstract Background and Purpose Overactivation of the alternative pathway (AP) underlies several diseases. Iptacopan is an oral, first‐in‐class, highly potent specific inhibitor of factor B, a key AP protease. Experimental Approach The analysis included data from two phase 1 randomised, volunteer‐blinded, placebo‐controlled studies: Study 1, a single ...
Irina Baltcheva +5 more
wiley +1 more source
Neuropathology and Applied Neurobiology, Volume 52, Issue 3, June 2026.Graphical summary of post‐mortem brain tissue findings that differ between symptomatic and asymptomatic AD. Current evidence suggests reduced accumulation of Aβ and p‐tau oligomers, particularly at synapses, preserved neuronal and synaptic integrity and metabolic activity and a dynamic profile of glial and immune responses in ASYMAD.
Thiago Guilherme Rêgo Barros +6 more
wiley +1 more source
Veterinary Dermatology, Volume 37, Issue 3, Page 353-364, June 2026.ABSTRACT Background Canine atopic dermatitis (cAD) is a multifactorial, inherited skin disease, estimated to affect ≤ 15% of dogs. Studies of skin messenger mRNA in cAD currently use invasive methods, including blood sampling and biopsy collection, whilst advances in human atopic dermatitis study methodology have demonstrated reliable use of minimally ...
Xavier Langon +5 more
wiley +1 more source
Veterinary Dermatology, Volume 37, Issue 3, Page 375-385, June 2026.ABSTRACT Background Advances in transcriptomics have driven the demand for minimally invasive, reproducible and high‐yield skin sampling methods, particularly for studying inflammatory skin diseases in companion animals. Hypothesis/Objectives We tested tolerability, feasibility and RNA quantity and quality of three minimally invasive skin sampling ...
Ina Herrmann +2 more
wiley +1 more source
ChemSusChem, Volume 19, Issue 10, 27 May 2026.Indoles are promising N‐heterocyclic liquid organic hydrogen carriers. Here, we investigate the reaction pathways of (methyl)indole (de)hydrogenation over Pd catalysts using reaction experiments and computational modeling: we show that distinct intermediates are formed in hydrogenation versus dehydrogenation steps, and stereocenter evolution is ...
Matthew D. Edgar +6 more
wiley +1 more source
Thermophysical Properties of the Desulphurization Slags With Various CaS and CaO/Al2O3 Ratio
Advanced Engineering Materials, Volume 28, Issue 10, 20 May 2026.This article investigates how CaS content and the CaO/Al2O3 ratio influence the thermophysical properties of desulphurization slags. Using experimental measurements and thermodynamic simulations, this study reveals complex effects on viscosity, surface tension, and density, providing new insight into slag structure and phase behavior under ...
Eldar Salpagarov +4 more
wiley +1 more source
Synthesis, Crystal Structure, and Optoelectronic Properties of [(n‐/tert‐C4H9)S(CH3)2]PbI3
European Journal of Inorganic Chemistry, Volume 29, Issue 15, 20 May 2026.Reaction of two isomers of butyldimethylsulfonium cation with PbI2 using solid‐state and solution methods yielded the corresponding organic/inorganic hybrid compounds with high humidity tolerance and 1D crystal structures of [n‐C4H9S(CH3)2]PbI3 and [tert‐C4H9S(CH3)2]PbI3.
Ioannis Koutsoumpogeras +4 more
wiley +1 more source