Results 151 to 160 of about 26,236 (223)

Human β‐Cell Dedifferentiation and Diabetes

Journal of Diabetes, Volume 18, Issue 10, October 2026.
Human β‐cell dedifferentiation is inversely associated with HOMA‐β and occurs in Type 2 diabetes, Type 3c diabetes, and age‐related diabetes, potentially before hyperglycemia develops. Progressive loss of β‐cell identity is accompanied by dedifferentiation and transdifferentiation, suggesting that reversing these cell‐state changes may help restore ...
Jiajun Sun, Jinsook Son, Qidi Wang
wiley   +1 more source

Assembly of Bioactive Superstructures via Metal–Phenolic Complexation for Blood Purification

Angewandte Chemie, Volume 138, Issue 40, 28 September 2026.
Bioactive superstructures are assembled via metal–phenolic‐mediated assembly on agarose templates, followed by modification with human serum albumin. These superstructures demonstrate high bilirubin adsorption efficiency, strong antibacterial activity, and anticoagulant activity, providing a strategy for the rational design of multifunctional blood ...
Po Wang, Jingqu Chen, Siying Chen, Binsha Peng, Zhifeng Zhou, Ling Zhang, Rui Xie, Xiaojie Ju, Wei Wang, Dawei Pan, Liangyin Chu, Frank Caruso, Zhuang Liu   +12 more
wiley   +2 more sources

Crystal structure and Hirshfeld surface analysis of 6-bromo-2-(penta-fluoro-phen-yl)-2,3,7,7a-tetra-hydro-3a,6-ep-oxy-isoindol-1(6<i>H</i>)-one. [PDF]

Acta Crystallogr E Crystallogr Commun
Maslova VS, Cherepanova VM, Khrustalev VN, Akkurt M, Manahelohe GM, Hasanov KI, Guliyeva NA.   +6 more
europepmc   +1 more source

Insights into the modulation of age‐related macular degeneration: Molecular and systems‐level perspectives

Acta Ophthalmologica, Volume 104, Issue S293, Page S4-S35, October 2026.
ENGLISH SUMMARY In developed countries, age‐related macular degeneration (AMD) is the leading cause of visual impairment in the aging population. Understanding of its pathogenesis is limited and the number of patients is predicted to continue rising. AMD is classified into two main forms: dry and neovascular AMD (dAMD and nAMD, respectively).
Hanna Heloterä
wiley   +1 more source

In Vitro Three-Dimensional Human Liver Model for Drug-Induced Liver and Bile Duct Injury Prediction. [PDF]

Toxics
Fu X, Hu J, Jiang X, Sun Y, Xiang W, Kuang R, Kang H, He L, Sang J.   +8 more
europepmc   +1 more source

Acute anaphylactic and multiorgan inflammatory effects of Comirnaty in pigs: evidence of spike protein mRNA transfection and paralleling inflammatory cytokine upregulation

British Journal of Pharmacology, Volume 183, Issue 20, Page 6225-6239, October 2026.
Abstract Background and Purpose Rare but severe adverse events (AEs) associated with mRNA‐lipid nanoparticle (LNP) COVID‐19 vaccines, such as Comirnaty, include anaphylaxis and inflammatory organ disorders, but their underlying mechanisms are poorly understood. We aimed to develop an animal model to study these phenomena.
László Dézsi, Gábor Kökény, Gábor Szénási, Csaba Révész, Tamás Mészáros, Bálint A. Barta, Réka Facsko, Anna Szilasi, Tamás Bakos, Gergely T. Kozma, Attila B. Dobos, Béla Merkely, Tamás Radovits, János Szebeni   +13 more
wiley   +1 more source

Understanding Surface Interfacial Phenomena During Tricalcium Silicate Dissolution From TEM and XRR

Journal of the American Ceramic Society, Volume 109, Issue 10, October 2026.
ABSTRACT Understanding the dissolution mechanism of tricalcium silicate (C3S) is essential for interpreting its reactivity in cementitious systems. While the dissolution mechanism of C3S has been considered to follow the classical leached‐layer model, the mechanism has also been proposed to occur through the coupled interfacial dissolution ...
Aidyn Tugelbayev, Hongyu Wang, David Jarret Wright, Jing Zhao, F. Marc Michel, Alexander S. Brand   +5 more
wiley   +1 more source

The C3-C3aR axis modulates trained immunity in alveolar macrophages. [PDF]

Elife
Earhart AP, Lopez AE, Hernandez JI, Nallapu A, Chavez D, Suthakaran S, Yang B, Hyun J, Aponte Alburquerque R, Starick M, Garnica L, Ozanturk AN, Maurya RK, Wu X, Haspel J, Lee JW, Hook J, Kulkarni HS.   +17 more
europepmc   +1 more source

Rapid Identification of Mineral Phases on Continuous‐Casting Stopper Rods via SEM–CL Analysis

Journal of the American Ceramic Society, Volume 109, Issue 10, October 2026.
ABSTRACT Although the identification of solidified liquid (12CaO·7Al2O3, 3CaO·Al2O3) and CaO·Al2O3 phases is critical for detecting stopper rod degradation, it is hindered by complex morphologies and the analytical effort required. We propose a rapid method for identifying mineral phases on alumina stopper rods used in continuous casting of Ca‐treated ...
Susumu Imashuku
wiley   +1 more source

Divergent roles of ent‐kaurene oxidase paralogs in rice momilactone biosynthesis

Journal of Integrative Plant Biology, Volume 68, Issue 10, Page 3776-3789, October 2026.
Rice contains a five‐gene tandem array of genes encoding members of the ent‐kaurene oxidase (KO) family, with OsKOL4 and OsKOL5 playing divergent roles in momilactone metabolism, but both acting in the production of antifungal and antibacterial phytoalexins, which are important for disease resistance.
Zhibiao Wang, Yiling Feng, Leiming You, Meimei Xu, Kristin Helwig, Riqing Li, Si Nian Char, Bing Yang, Reuben J. Peters   +8 more
wiley   +1 more source