Results 131 to 140 of about 26,236 (223)
Endotoxins and Biological Implications—Review
Graphical overview of endotoxin sources, exposure routes, biological effects, detection methods, and routes of elimination. ABSTRACT Endotoxins, also known as lipopolysaccharides (LPSs), are structural components of the outer membrane of Gram‐negative bacteria and some cyanobacteria.
Uzair Ishtiaq +5 more
wiley +1 more source
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos +4 more
wiley +1 more source
Adaptive Immunity in Marsupials
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol +2 more
wiley +1 more source
Novel 1‐(1‐benzyl‐2‐oxoindolin‐3‐ylidene)thiosemicarbazides (6a–l) bearing a 3‐sulfamoylphenyl moiety selectively inhibited the tumor‐associated hCA IX and XII isoforms over hCA I and II isoforms at the nanomolar levels. Compounds 6k and 6f emerged as the most potent inhibitors of hCA IX and XII, respectively.
Çağla Begüm Apaydın +3 more
wiley +1 more source
A self‐powered phase‐encoding sensing paradigm enables direct motion‐to‐time information conversion, providing a compact and autonomous strategy for high resolution angular displacement measurement. ABSTRACT In modern manufacturing and engineering, angular displacement sensors are crucial for motion control and feedback systems in Electromechanical ...
Shuxian Wang +3 more
wiley +1 more source
Increase in prostanoid formation in rat liver macrophages (Kupffer cells) by human anaphylatoxin C3a
Human anaphylatoxin C3a increases glycogenolysis in perfused rat liver. This action is inhibited by prostanoid synthesis inhibitors and prostanoid antagonists.
Dieter, Peter +3 more
core
Abstract Alzheimer's disease (AD) is accompanied by persistent disturbances in brain energy metabolism, and microglial glucose metabolic reprogramming constitutes an important link among pathological protein deposition, neuroinflammation, and impaired clearance.
Yuan Chen +8 more
wiley +1 more source
Two‐Photon Absorption in Perovskite Semiconductors
The two‐photon absorption (TPA) models used for perovskite semiconductors were primarily developed for conventional semiconductors and neglect the unique perovskite band structure. We have developed a model for the perovskite TPA coefficient, incorporating the inter‐ and intra‐band transitions in the conduction band states.
David Ompong +6 more
wiley +1 more source
Sickle cell disease inflammation emerges from interconnected cytokine networks. Immune‐informatics integrates multi‐omics, network biology and artificial intelligence to decode inflammatory signatures, predict complications and identify precision therapeutic targets. Abstract Background Sickle cell disease (SCD) is characterised by chronic inflammation
Emmanuel Ifeanyi Obeagu +1 more
wiley +1 more source
This study leverages complete plastid and nuclear ribosomal DNA sequences from 40 species to resolve the complex phylogeny and organellar genome evolution of the diverse plant tribe Elatostemateae. The analysis uncovered significant plastome structural variations, including novel inversions and a rare mitochondrial DNA integration event, and identified
Long‐Fei Fu +5 more
wiley +1 more source

