Regioselective Formation of α-Vinylpyrroles from the Ruthenium-Catalyzed Coupling Reaction of Pyrroles and Terminal Alkynes Involving C–H Bond Activation [PDF]
, 2010 The cationic ruthenium catalyst Ru3(CO)12/NH4PF6 was found to be highly effective for the intermolecular coupling reaction of pyrroles and terminal alkynes to give gem-selective α-vinylpyrroles.
Gao, Ruili, Yi, Chae S.
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Complement effectors, C5a and C3a, in cystic fibrosis lung fluid correlate with disease severity. [PDF]
PLoS ONE, 2017 In cystic fibrosis (CF), lung damage is mediated by a cycle of obstruction, infection, inflammation and tissue destruction. The complement system is a major mediator of inflammation for many diseases with the effectors C5a and C3a often playing important
Pamela S Hair +5 more
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Discovery of functionally selective C5aR2 ligands: novel modulators of C5a signalling. [PDF]
, 2016 The complement cascade is comprised of a highly sophisticated network of innate immune proteins that are activated in response to invading pathogens or tissue injury. The complement activation peptide, C5a, binds two seven transmembrane receptors, namely
Blaskovich, M.A. +11 more
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Aquaculture Reports, 2023 Death of grass carp (Ctenopharyngodon idella) caused by grass carp reovirus (GCRV) infection severely restricts the development of the grass carp industry.
Baohong Xu +8 more
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1,2-Dimethyl-4,5-diphenylbenzene determined on a Bruker SMART X2S benchtop crystallographic system [PDF]
, 2009 The title compound, C(20)H(18), has two crystallographically independent molecules in the asymmetric unit. The phenyl substituents of molecule A are twisted away from the plane defined by the central benzene ring by 131.8 (2) and -52.7 (3)degrees.
Briggs, Jonathan B +2 more
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Increased local concentration of complement C5a contributes to incisional pain in mice
Journal of Neuroinflammation, 2011 Background In our previous study, we demonstrated that local injection of complement C5a and C3a produce mechanical and heat hyperalgesia, and that C5a and C3a activate and sensitize cutaneous nociceptors in normal skin, suggesting a contribution of ...
Clark David J +5 more
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Perturbative Finite-Temperature Results and Pad'e Approximants [PDF]
, 1997 Pad'e approximants are used to improve the convergence behavior of perturbative results in massless scalar and gauge field theories at finite temperature.Comment: 11 pages, LaTeX, incl.
Kastening, Boris
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Complement Activation in Arterial and Venous Thrombosis is Mediated by Plasmin
EBioMedicine, 2016 Thrombus formation leading to vaso-occlusive events is a major cause of death, and involves complex interactions between coagulation, fibrinolytic and innate immune systems.
Jonathan H. Foley +8 more
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p38MAPK, ERK and PI3K signaling pathways are involved in C5a-primed neutrophils for ANCA-mediated activation. [PDF]
PLoS ONE, 2012 BACKGROUND: The complement system is one of the important contributing factors in the development of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).
Jian Hao +4 more
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Benefit of Apabetalone on Plasma Proteins in Renal Disease. [PDF]
, 2018 Introduction:Apabetalone, a small molecule inhibitor, targets epigenetic readers termed BET proteins that contribute to gene dysregulation in human disorders. Apabetalone has in vitro and in vivo anti-inflammatory and antiatherosclerotic properties.
Gilham, Dean +11 more
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