Results 21 to 30 of about 51,606 (244)

A pro-inflammatory role of C5L2 in C5a-primed neutrophils for ANCA-induced activation. [PDF]

PLoS ONE, 2013
BACKGROUND:The complement system is crucial for the development of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). In particular, C5a and its receptor on neutrophils, CD88, play a central role.
Jian Hao, Chen Wang, Jun Yuan, Min Chen, Ming-Hui Zhao   +4 more
doaj   +1 more source

Trithiacyanuric acid: a second triclinic polymorph [PDF]

, 2010
The title compound, C3H3N3S3, is a triclinic modification. The other reported modification crystallizes with just one molecule in the asymmetric unit, [Guo et al. (2006). Cryst. Growth Des.
Brito, Iván, Albanez, Joselyn, Bolte, Michael   +2 more
core   +2 more sources

Correlation of serum complement factor 5a level with inflammatory response and cognitive function in patients with Alzheimer’s disease of different severity

BMC Neurology, 2023
Background Alzheimer’s disease (AD) is a common cause of dementia. Serum complement factor 5a (C5a) is exceedingly implicated in AD. We explored the role of C5a levels in AD patients of different severity.
Zhilian Li, Huifang Wu, Yi Luo, Xianpei Tan   +3 more
doaj   +1 more source

Pertussis Toxin-sensitive Activation of Phospholipase C by the C5a and fMet-Leu-Phe Receptors [PDF]

, 1996
Signal transduction pathways that mediate C5a and fMet-Leu-Phe (fMLP)-induced pertussis toxin (PTx)-sensitive activation of phospholipase C (PLC) have been investigated using a cotransfection assay system in COS-7 cells.
Jiang, Huiping, Kuang, Yanan, Simon, Melvin I., Smrcka, Alan, Wu, Dianqing, Wu, Yanping   +5 more
core   +1 more source

Different concentrations of C5a affect human dental pulp mesenchymal stem cells differentiation

BMC Oral Health, 2021
Background During the process of deep decay, when decay approaches the pulp, an immune response is triggered inside the pulp, which activates the complement cascade.
Jie Liu, Xiaoling Wei, Junlong Hu, Xiaohan Tan, Xiaocui Kang, Li Gao, Ning Li, Xin Shi, Mengtong Yuan, Weiping Hu, Mingyue Liu   +10 more
doaj   +1 more source

Synthesis of 2-Acylphenol and Flavene Derivatives from the Ruthenium-Catalyzed Oxidative C-H Acylation of Phenols with Aldehydes [PDF]

, 2015
The cationic ruthenium hydride complex [(C6H6)(PCy3)(CO)RuH]+BF4− has been found to be an effective catalyst for the oxidative C–H coupling reaction of phenols with aldehydes to give 2-acylphenol compounds.
Aponick, Arockiam, Baslé, Boots, Chan, Charest, Choy, Fristrup, González-Bello, Gore, Gunanathan, Han, Jia, Kakiuchi, Kakiuchi, Kandaswami, Koren-Selfridge, Kwon, Lee, Li, Li, Li, Li, Lyons, Madabhushi, Miyaura, Mo, Ngidi, Obora, Olah, Park, Pastine, Rao, Rappoport, Shan, Sharma, Sigman, Suzuki, Tang, Thirunavukkarasu, Thirunavukkarasu, Thirunavukkarasu, Wang, Yang, Yao, Yeung, Zhang, Álvarez-Bercedo   +47 more
core   +2 more sources

A recombinant vaccine effectively induces c5a-specific neutralizing antibodies and prevents arthritis. [PDF]

PLoS ONE, 2010
OBJECTIVES: To develop and validate a recombinant vaccine to attenuate inflammation in arthritis by sustained neutralization of the anaphylatoxin C5a. METHODS: We constructed and expressed fusion protein of C5a and maltose binding protein.
Kutty Selva Nandakumar, Asa Jansson, Bingze Xu, Niclas Rydell, Parvin Ahooghalandari, Lars Hellman, Anna M Blom, Rikard Holmdahl   +7 more
doaj   +1 more source

Local endothelial complement activation reverses endothelial quiescence, enabling t-cell homing, and tumor control during t-cell immunotherapy

OncoImmunology, 2017
Cancer immunotherapy relies upon the ability of T cells to infiltrate tumors. The endothelium constitutes a barrier between the tumor and effector T cells, and the ability to manipulate local vascular permeability could be translated into effective ...
Andrea Facciabene, Francesco De Sanctis, Stefano Pierini, Edimara S. Reis, Klara Balint, John Facciponte, Jens Rueter, Masahiro Kagabu, Paola Magotti, Evripidis Lanitis, Robert A. DeAngelis, Ronald J. Buckanovich, Wenchao C. Song, John D. Lambris, George Coukos   +14 more
doaj   +1 more source

Complement 3a and Complement 5a as Biochemical Markers in Diabetic Nephropathy [PDF]

International Journal of Medical Arts
Background: Diabetes mellitus [DM] is growing into a global epidemic and diabetic nephropathy [DN] is one of its most feared complications. Inflammation is an important mechanism in the pathogenesis of DN and many studies have pointed to anaphylatoxins ...
Safwat Ahmed, Alsayed Alsayed, Mohammed Aref, Ahmad Alkot   +3 more
doaj   +1 more source

1,5-Bis(4-nitrophenoxy)pentane [PDF]

, 2009
The title compound, C17H18N2O6, crystallizes with two molecules in the asymmetric unit. In both molecules, one of the C-C bonds of the pentamethylene chain connecting the two aromatic rings is in a trans conformation and another displays a gauche ...
Muhammad Saif Ullah Khan, Zareen Akhter, Michael Bolte, M. Saeed Butt, Humaira M. Siddiqi, Faghihi, Hsiao, Hsiao, Mehdipour-Ataei, Mehdipour-Ataei, Schab-Balcerzak, Shao, Sheldrick, Spek   +13 more
core   +1 more source