Results 31 to 40 of about 51,606 (244)

By Increasing the Expression and Activation of STAT3, Sustained C5a Stimulation Increases the Proliferation, Migration, and Invasion of RCC Cells and Promotes the Growth of Transgrafted Tumors

Cancer Management and Research, 2021
Jing-Min Zheng,1,* Han-Xi Zhou,1,* Hong-Yuan Yu,1,* Yu-Hui Xia,2 Qing-Xin Yu,2 Hang-Shuai Qu,1 Jia-Qian Bao1 1Department of Urology, Taizhou Hospital, Wenzhou Medical University, Linhai, Zhejiang, People’s Republic of China; 2Department of ...
Zheng JM, Zhou HX, Yu HY, Xia YH, Yu QX, Qu HS, Bao JQ   +6 more
doaj  

4-Nitro­phenyl 2-methyl­benzoate [PDF]

, 2009
The title compound, C14H11NO4, crystallizes with two mol­ecules in the asymmetric unit. The major conformational difference between these two mol­ecules is the dihedral angle between the aromatic rings, namely 36.99 (5) and 55.04 (5)°.
Bibi, Uzma, Siddiqi, Humaira Masood, Bolte, Michael, Akhter, Zareen   +3 more
core   +2 more sources

Detection of the complement fragment C5a in inflammatory exudates from the rabbit peritoneal cavity using radioimmunoassay. [PDF]

, 1983
We describe a radioimmunoassay for rabbit C5a and its use to obtain evidence of extravascular C5a generation in two inflammatory reactions in the peritoneal cavity.
Forrest, MJ, Jose, PJ, Williams, TJ
core   +2 more sources

C5a elevation in convalescents from severe COVID-19 is not associated with early complement activation markers C3bBbP or C4d

Frontiers in Immunology, 2022
Numerous publications have underlined the link between complement C5a and the clinical course of COVID-19. We previously reported that levels of C5a remain high in the group of severely ill patients up to 90 days after hospital discharge.
Daria Kowalska, Alicja Kuźniewska, Yaiza Senent, Yaiza Senent, Yaiza Senent, Beatriz Tavira, Beatriz Tavira, Beatriz Tavira, Susana Inogés, Susana Inogés, Susana Inogés, Ascensión López-Díaz de Cerio, Ascensión López-Díaz de Cerio, Ascensión López-Díaz de Cerio, Ruben Pio, Ruben Pio, Ruben Pio, Ruben Pio, Marcin Okrój, José Ramón Yuste, José Ramón Yuste, José Ramón Yuste   +21 more
doaj   +1 more source

Four related benzazepine derivatives in a reaction pathway leading to a benzazepine carboxylic acid : hydrogen-bonded assembly in zero, one, two and three dimensions [PDF]

, 2014
The authors thank ‘Centro de Instrumentacion Cientıfico-Tecnica of Universidad de Jaen’ and the staff for data collection. AP, SAG and CMS thank Colciencias for financial support (grant No. 1102–521–28229). JC thanks the Consejerıa de Innovacion, Ciencia
Cobo, J., Glidewell, C., Guerrero, S.A., Palma, A., Sanabría, C.M.   +4 more
core   +2 more sources

A disturbed balance between blood complement protective factors (FH, ApoE) and common pathway effectors (C5a, TCC) in acute COVID-19 and during convalesce

Scientific Reports, 2022
A complement effect on homeostasis during infection is determined by both cytotoxic (activate complement component 5 (C5a) terminal cytotoxic complex (TCC)), and cytoprotective elements (complement factor H (FH), as well as apolipoprotein E (ApoE)). Here,
Krzysztof Laudanski, Tony Okeke, Kumal Siddiq, Jihane Hajj, Mariana Restrepo, Damodar Gullipalli, Wen-chao Song   +6 more
doaj   +1 more source

A peptide mimic of the chemotaxis inhibitory protein of Staphylococcus aureus: towards the development of novel anti-inflammatory compounds [PDF]

, 2010
Complement factor C5a is one of the most powerful pro-inflammatory agents involved in recruitment of leukocytes, activation of phagocytes and other inflammatory responses.
AJ Wright, Anton Bunschoten, B Postma, B Postma, BO Gerber, Carla J. C. de Haas, CE Stotz, DE Epps van, F Blanco, H Lee, J Cavanagh, JH Ippel, JJ Chen, Johan Kemmink, Johannes H. Ippel, John A. W. Kruijtzer, KE Veldkamp, LM Proctor, Louris Feitsma, M Allegretti, M Farzan, PJ Haas, PN Monk, RF Guo, Rob M. J. Liskamp, TS Haque, ZG Chen   +26 more
core   +1 more source

C5a enhances dysregulated inflammatory and angiogenic responses to malaria in vitro: potential implications for placental malaria. [PDF]

PLoS ONE, 2009
Placental malaria (PM) is a leading cause of maternal and infant mortality. Although the accumulation of parasitized erythrocytes (PEs) and monocytes within the placenta is thought to contribute to the pathophysiology of PM, the molecular mechanisms ...
Andrea Conroy, Lena Serghides, Constance Finney, Simon O Owino, Sanjeev Kumar, D Channe Gowda, W Conrad Liles, Julie M Moore, Kevin C Kain   +8 more
doaj   +1 more source

Intermolecular Dehydrative Coupling Reaction of Arylketones with Cyclic Alkenes Catalyzed by a Well-Defined Cationic Ruthenium-Hydride Complex: A Novel Ketone Olefination Method via Vinyl C–H Bond Activation [PDF]

, 2010
The cationic ruthenium−hydride complex [(η6-C6H6)(PCy3)(CO)RuH]+BF4− was found to be a highly effective catalyst for the intermolecular olefination reaction of aryl ketones with cycloalkenes.
Lee, Do W., Yi, Chae S.
core   +2 more sources

The complement anaphylatoxin C5a induces apoptosis in adrenomedullary cells during experimental sepsis. [PDF]

PLoS ONE, 2008
Sepsis remains a poorly understood, enigmatic disease. One of the cascades crucially involved in its pathogenesis is the complement system. Especially the anaphylatoxin C5a has been shown to have numerous harmful effects during sepsis.
Michael A Flierl, Daniel Rittirsch, Anthony J Chen, Brian A Nadeau, Danielle E Day, J Vidya Sarma, Markus S Huber-Lang, Peter A Ward   +7 more
doaj   +1 more source