Results 101 to 110 of about 26,236 (223)

IgE‐Binding Bacterial Components Not Yet Documented in the Allergen Databases and Their Allergenic Mechanisms: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe, Marua Abu Risha, Ioana Agache, Claus Bachert, Barbara Bröker, Riccardo Castagnoli, Gabriele Gadermaier, Richard E. Goodman, Amir Guemari, Christiane Hilger, Alain Jacquet, Sabine Kespohl, Ludger Klimek, Annette Kuehn, Jonas Lidholm, Vera Mahler, Markus Ollert, Thomas A. Platts‐Mills, Monika Raulf, Peter Schmid‐Grendelmeier, Frieder Schmiedeke, Marianne van Hage, Joana Vitte, Josefina Zakzuk, Anna Pomés   +24 more
wiley   +1 more source

Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1

, 2003
Complement has recently been implicated in developmental pathways and noninflammatory processes. The expression of various complement components and receptors has been shown in a wide range of circulating myeloid and lymphoid cells, but their role in ...
L. A, J. D. AND RATAJCZAK M. Z., MASTELLOS, D, M, SPRUCE, RECA, R, MAREK HONCZARENKO, JANOWSKA WIECZOREK, RATAJCZAK, J, A, LAMBRIS, MARQUEZ, L, GLODEK, A, MAJKA, M, FRANCHINI, Silvia   +12 more
core   +1 more source

In Xenopus oocytes the human C3a and C5a receptors elicit a promiscuous response to the anaphylatoxins [PDF]

, 1996
The Xenopus laevis oocyte has been widely utilized for cloning and functional expression of G-protein coupled receptors (GPCR). This system was used for the functional expression and characterization of the recently identified human C3a receptor ...
Robert S Ames, Paru Nuthulaganti, Nuthulaganti, Paru, Chandrika Kumar, Kumar, Chandrika, Ames, Robert S   +5 more
core   +1 more source

Cfd promotes adipocyte differentiation through C3a-C3aR activation.

, 2016
(A) Increased C3a production was observed in Cfd stably overexpressing 3T3-L1 cells. Media was collected from control or Cfd overexpressing cells and C3a content was measured by ELISA as described in methods.
Ui Jeong Yun (3111426), Seo-Hyuk Chang (3111417), No-Joon Song (3111423), Dean Y. Li (46432), Kye Won Park (785952), Hironori Waki (200172), Peter Tontonoz (165319), Suji Kim (1807360), Ki-Moon Park (3111420), Byung-Hyun Jang (3111429)   +9 more
core   +1 more source

Kininase I drives angiotensin II‐induced hypertension through activation of the bradykinin B1 receptor

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Kininase I, comprising carboxypeptidase N (CPN) and carboxypeptidase M, regulates kinin activity and is up‐regulated during injury, inflammation and immune activation. Under these conditions, kininase I converts bradykinin and kallidin into des‐Arg kinins, primary endogenous agonists of the bradykinin B1 receptor (R ...
Acacia White, Drew Theobald, Alexandra Johnston, David A. Tulis, Johanna Hannan, Srinivas Sriramula   +5 more
wiley   +1 more source

Influence of quartz surfaces on the reaction C3A + CaSO4.2H2O + water INFLUENCE OF QUARTZ SURFACES ON THE REACTION C3A + CaSO4.2H20 + WATER

, 1977
Quartz surfaces counteract the retarding action of SO~-on the hydration of C3A, by presenting additional sites for ettringite crystallization. Strong retardation requires the presence of ettringite near the C3A , influencing the local concentrations ...
C L M Holten, H N Stein
core  

Shared dysregulation of complement and phosphorylation pathways in the cerebrospinal fluid of encephalitis, Aicardi–Goutières syndrome, and autism

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To identify shared and disorder‐specific molecular alterations across encephalitis, Aicardi–Goutières syndrome (AGS), and autism spectrum disorder (ASD) using cerebrospinal fluid (CSF) proteomics. Method In this cross‐sectional case–control study, mass‐spectrometry‐based proteomics was performed on archived CSF samples collected between ...
Omar H. Shadid, Peter G. Hains, Velda X. Han, Jingya Yan, Michael Griffiths, Ignatius Pang, Sushil Bandodkar, Phillip J. Robinson, Russell C. Dale   +8 more
wiley   +1 more source

Determination of the C3a generation by B. valaisiana.

, 2013
Spirochetes (6×106) were incubated with 25% of NHS for 5 min at 21°C and activation of C3 was then analyzed by the MicroVue C3a Plus ELISA. Generated C3a was detected using a monoclonal anti-C3a capture antibody and a HRP-conjugated polyclonal anti-C3 ...
Peter Kraiczy (36173), Jasmin Schwab (105418), Christine Skerka (105424), Reinhard Wallich (57833), Claudia Hammerschmidt (105420), Dania Richter (105422), Peter F. Zipfel (105431), Franz-Rainer Matuschka (105426)   +7 more
core   +1 more source

Molecular dynamics simulations and fluorescence spectroscopy suggest reduced tryptophan‐to‐heme energy transfer facilitates lignin degradation in ClassII peroxidases

The FEBS Journal, EarlyView.
In lignin peroxidase and versatile peroxidase, low FRET from buried Trp to heme promotes long‐range electron transfer (LRET) from substrate to heme. This efficient electron flow is facilitated by reduced FRET competition. This mechanism likely evolved to enable the effective degradation of bulky, high‐redox‐potential lignin that cannot reach the enzyme'
Yi Ren, Dale Ang, Haluk Ertan, Anne Poljak, Janice R. Aldrich‐Wright, Wallace J. Bridge, Khawar Sohail Siddiqui   +6 more
wiley   +1 more source

Teacher Well‐Being Across Career Stages: An Ecological Study of Early‐ and Mid‐Career English Teachers in Japanese Secondary Schools

International Journal of Applied Linguistics, EarlyView.
ABSTRACT Teacher well‐being has garnered increasing attention in language education, as it plays a vital role in shaping both their professional lives and student learning. Although its importance is recognised, further research is still needed to gain a more comprehensive understanding of language teachers' well‐being.
Takeshi Onodera
wiley   +1 more source