Results 41 to 50 of about 364,632 (296)

A Sensitivity Analysis on the Spectral Signatures of Low-Backscattering Sea Areas in Sentinel-1 SAR Images

open access: yesRemote Sensing, 2021
Satellite synthetic aperture radar (SAR) is a unique tool to collect measurements over sea surface but the physical interpretation of such data is not always straightforward. Among the different sea targets of interest, low-backscattering areas are often
Valeria Corcione   +3 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Base-mediated C4-selective C-H-sulfonylation of pyridine

open access: yes, 2022
The direct regioselective C-H-functionalization of simple, unfunctionalized pyridines is considered a long-standing challenge in heterocyclic chemistry.
Marius, Friedrich, Georg, Manolikakes
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Evaluation of Fungicides and Management Strategies against Cercospora Leaf Spot of Olive Caused by Pseudocercospora cladosporioides

open access: yesAgronomy, 2020
Cercospora leaf spot of olive (CLSO), caused by Pseudocercospora cladosporioides, is one of the most important foliar diseases of olives worldwide. This study aimed to evaluate the effect of a wide range of fungicides on mycelial growth and conidial ...
Joaquín Romero   +4 more
doaj   +1 more source

Nitrogen and water use efficiency of C4 plants

open access: yes, 2011
Species with the C4 photosynthetic pathway have evolved biochemical CO2 concentrating mechanisms that allow Rubisco to function in a high CO2 environment. This increases both their nitrogen and water use efficiency compared to C3 species.
Evans, John R.   +4 more
core   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran   +13 more
wiley   +1 more source

Sea State Monitoring by Ship Motion Measurements Onboard a Research Ship in the Antarctic Waters

open access: yesJournal of Marine Science and Engineering, 2021
A parametric wave spectrum resembling procedure is applied to detect the sea state parameters, namely the wave peak period and significant wave height, based on the measurement and analysis of the heave and pitch motions of a vessel in a seaway, recorded
Silvia Pennino   +10 more
doaj   +1 more source

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi   +8 more
wiley   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo   +88 more
wiley   +1 more source

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