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The Goldilocks paradox: when partial oncoprotein inhibition fuels metastasis in Ewing sarcoma
Targeting oncogenic fusion proteins remains a major challenge in pediatric oncology. In this issue of EMBO Molecular Medicine, Suresh et al (2025) demonstrate that incomplete inhibition of EWS::FLI1 in Ewing sarcoma paradoxically promotes metastatic ...
Marie Castets +2 more
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The Functional Significance of the Rho/Rho-Kinase Pathway in Human Erythrocytes
OBJECTIVE: Erythrocyte deformability, which can be influenced by various intracellular signaling mechanisms, such as nitric oxide, cAMP, cGMP, and protein kinases, is the most important physiological factor providing the blood flow in microcirculation ...
R. Nalan Tiftik +3 more
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There has been no previous systematic study of bullous skin diseases with granular basement membrane zone deposition exclusively of C3. In this study we collected 20 such patients, none of whom showed cutaneous vasculitis histopathologically. Oral dapsone and topical steroids were effective.
Hashimoto, Takashi +15 more
openaire +3 more sources
A Causal Model of Consumer-Based Brand Equity
Branding literature suggests that consumer-based brand equity (CBBE) is a multidimensional construct. Starting from this approach and developing a conceptual multidimensional model, this study finds that CBBE can be best modelled with a two-dimensional ...
Szőcs Attila, Berács József
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The Effect of Economic Policies on Agricultural and Industrial Exports of Iran [PDF]
International trade expansion and export development have been the center of attention by the economists, policy makers and the cornerstone of planning in many countries of the world.
Fatemeh Alijani +3 more
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Market Synchronicity Among African Markets: is IFRS Adoption an Augmentor or Inhibitor?
This paper investigates the dynamics of market synchronicity and International Financial Reporting Standards (IFRS) adoption in Africa. It seeks to determine whether or not IFRS is an augmentor or inhibitor of market synchronicity in Africa.
Queku Yaw Ndori +5 more
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Econometrics is a branch of economics that uses mathematical and statistical methods to study quantitative and qualitative relationships within economic phenomena.
Omir Ainur +4 more
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The Impact of Education on Energy Poverty: Empirical Evidence from Vietnam
In the era of industrialization and modernization, energy is always a key factor in creating a breakthrough. In contrast to the constantly increasing demand for energy, shortages or “energy poverty” are increasingly widespread.
Duong Truong Thi Thuy +5 more
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