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C3 glomerulopathy (C3G) is a rare kidney disease that causes kidney dysfunction as a result of dysregulation of the complement system alternate pathway (AP). C3G encompasses 2 separate disorders, C3 glomerulonephritis and dense deposit disease. The presentation and natural history is variable and kidney biopsy is needed to confirm the diagnosis.
Ali, Mehdi, Jonathan J, Taliercio
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Characterization of C3 in C3 glomerulopathy [PDF]
Abstract Background: C3 glomerulopathy (C3G) is caused by overactivity of the alternative pathway of complement that results in bright glomerular C3 staining with minimal or no deposition of immunoglobulins on immunofluorescence microscopy.
Sanjeev, Sethi +7 more
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Numerous investigators have studied the potential genetic causes of essential hypertension, and several genes have been described as candidates.1,2 These genes may contribute to the inappropriate and exaggerated growth of arterial smooth muscle cells in genetically hypertensive individuals and thus ultimately contribute to the disease by supporting ...
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AbstractIn this paper, we provide some characterizations of semisimple rings, right V-rings, right hereditary and regular right FGC-rings in terms of C3-modules. The notions of C3-envelope and C3-cover are introduced.
Atani Shahabaddin Ebrahimi +2 more
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C3 glomerulopathy is a recently defined entity that encompasses a group of kidney diseases caused by abnormal control of complement activation with deposition of complement component C3 in glomeruli leading to variable glomerular inflammation. Before the recognition of the unique pathogenesis of these cases, they were variably classified according to ...
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Referring to the developed and presented in previous publications (e.g. Barańska 2011) two-stage algorithm for real estate valuation, this article addresses the problem of the relationship between the two stages of the algorithm. An essential part of the
Barańska Anna, Nowak Dominika
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Modelling CAR Export from Slovakia to the United Kingdom - Vector Error Correction Approach
The aim of the article is to identify determinants of export of road vehicles from Slovakia to the United Kingdom. The Error correction model is based on monthly data from January 2008 to November 2018. The modelling identifies short and long-run effects
Pitoňáková Renáta
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Mucospheres produced by a mixotrophic protist impact ocean carbon cycling
Marine microbes govern ocean productivity and biogeochemistry, regulating global climate. Here the authors describe the sophisticated feeding strategy of a mixotrophic dinoflagellate and show how its behaviour impacts the vertical flux of carbon.
Michaela E. Larsson +7 more
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Reinforcement Learning with Probabilistic Boolean Network Models of Smart Grid Devices
The area of smart power grids needs to constantly improve its efficiency and resilience, to provide high quality electrical power in a resilient grid, while managing faults and avoiding failures.
Pedro Juan Rivera Torres +3 more
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A non-parametric model: free analysis of actigraphic recordings of acute insomnia patients
Both parametric and non-parametric approaches to time-series analysis have advantages and drawbacks. Parametric methods, although powerful and widely used, can yield inconsistent results due to the oversimplification of the observed phenomena.
Arlex Marín-García +4 more
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