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C3 glomerulopathy (C3G) is a rare kidney disease that causes kidney dysfunction as a result of dysregulation of the complement system alternate pathway (AP). C3G encompasses 2 separate disorders, C3 glomerulonephritis and dense deposit disease. The presentation and natural history is variable and kidney biopsy is needed to confirm the diagnosis.
Ali, Mehdi, Jonathan J, Taliercio
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Characterization of C3 in C3 glomerulopathy [PDF]
Abstract Background: C3 glomerulopathy (C3G) is caused by overactivity of the alternative pathway of complement that results in bright glomerular C3 staining with minimal or no deposition of immunoglobulins on immunofluorescence microscopy.
Sanjeev, Sethi +7 more
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Complement C3 recognition by C3 convertases. [PDF]
Abstract The complement system plays a fundamental role in human immunity, and its dysregulation is implicated in numerous diseases. Activation of the complement occurs through three main pathways: classical, lectin, and alternative; which converge at the central component, C3.
Jia C, Yang X, Zhao MH, Tan Y, Xiao J.
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Numerous investigators have studied the potential genetic causes of essential hypertension, and several genes have been described as candidates.1,2 These genes may contribute to the inappropriate and exaggerated growth of arterial smooth muscle cells in genetically hypertensive individuals and thus ultimately contribute to the disease by supporting ...
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Research background: The search for stable factors affecting latent variables that reflect the assessment of quality of life in three areas of an individual’s functioning is the background of the study.
Stanimir Agnieszka
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Increased C3 productivity in Midwestern lawns since 1982 revealed by carbon isotopes in Amanita thiersii [PDF]
How climate and rising carbon dioxide concentrations (pCO2) have influenced competition between C3 and C4 plants over the last 50 years is a critical uncertainty in climate change research.
Craine, Joseph M. +4 more
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Correlation Analysis in the Process of Weighting Real Property Attributes
The key goal of the market analysis carried out for property valuation purposes is to select pricing attributes of real properties and to assign so-called weights to them, which would illustrate their influence on the prices in a given market (Regulation
Barańska Anna Marta
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All of the world’s seven species of marine turtle are threatened by a multitude of anthropogenic pressures across all stages of their life history. The Calamian Islands, Palawan, Philippines provide important foraging and nesting grounds for four species:
Christopher N.S. Poonian +2 more
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C3 glomerulopathy is a recently defined entity that encompasses a group of kidney diseases caused by abnormal control of complement activation with deposition of complement component C3 in glomeruli leading to variable glomerular inflammation. Before the recognition of the unique pathogenesis of these cases, they were variably classified according to ...
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Corporate Governance and Financial Performance Nexus: Any Bidirectional Causality?
Most studies on corporate governance recognize endogeneity in the nexus between corporate governance and financial performance. Little attention has, however, been paid to the direction of causality between the two phenomena, and hence the Vector Error ...
Alley Ibrahim S. +2 more
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