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The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements. They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
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Abstract C53: rVP1 inhibits prostate cancer metastasis via suppression of Jagged1
Cancer Research, 2013Abstract Jagged1, a NOTCH ligand, has been shown to correlate with poor prognosis and metastasis of prostate cancer (CaP). CaP is a leading cause of cancer death among men worldwide. There is currently no effective therapeutic strategy for patients with castration-resistant prostate cancer (CRPC) which is defined as continued growth of ...
Jui-Ling Wang +4 more
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The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements. They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
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C53-29 Severe Methemoglobinemia Following Oral Ingestion of Amyl Nitrite
American Journal of Respiratory and Critical Care MedicineAbstract Introduction Amyl nitrite is a volatile alkyl nitrite known as “poppers”; when used recreationally, they promote states of euphoria and vasodilation. Reports of methemoglobinemia associated with poppers appear to be rising, yet oral ingestion remains underrecognized. We describe a case
S Joseph +3 more
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C53-32 Severe Systemic Lidocaine Toxicity Following Tumescent Liposuction
American Journal of Respiratory and Critical Care MedicineAbstract With the growing popularity of cosmetic surgery, liposuction has become one of the most commonly performed outpatient procedures. The tumescent technique—the most widely used approach—involves infiltration of large volumes of a dilute local anesthetic solution, often referred to as Klein’s solution. This formulation typically
B Wilson, T Soares, K Plowman, C Ruthman
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C53-15 Management of Iatrogenic Fentanyl Toxicity: A Case Report
American Journal of Respiratory and Critical Care MedicineAbstract Introduction Parenteral opiates are frequently administered in hospital settings. They are considered high-risk medications with potential for dangerous administration errors. Fentanyl, a highly lipophilic opioid, provides potent analgesia but can cause life-threatening effects such as
K Pais +4 more
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C53-13 Methotrexate and Trimethoprim-Sulfamethoxazole Interaction Causing Severe Pancytopenia
American Journal of Respiratory and Critical Care MedicineAbstract Methotrexate (MTX) is a cornerstone therapy for inflammatory and neoplastic conditions, but its use is limited by toxicities such as pancytopenia. These risks are magnified by drug interactions, particularly with trimethoprim-sulfamethoxazole (TMP-SMX), a sulfonamide antibiotic with overlapping antifolate activity and ...
M Mina, M Plascencia, C Erb, B Butler
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C53-05 Persistent Encephalopathy Following Lithium Toxicity: SILENT Syndrome
American Journal of Respiratory and Critical Care MedicineAbstract Lithium is an effective mood stabilizer but carries a narrow therapeutic index. Toxicity may develop with dehydration, renal impairment, or polypharmacy and can manifest as tremor, ataxia, or encephalopathy. Although most patients recover once lithium levels normalize, a subset experience persistent neurologic deficits ...
D Thota +5 more
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C53-18 A Case of Cocaine-induced Thrombotic Microangiopathy and Uncontrolled Hypertension
American Journal of Respiratory and Critical Care MedicineAbstract Introduction We present a case of a 36-year-old male with history of cocaine use who presented to the emergency department (ED) in hypertensive emergency, severe acute kidney failure, normocytic anemia, and thrombocytopenia. Kidney biopsy was ultimately performed, revealing evidence of
S Ahmed +4 more
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C53-10 Tcd Evidence Of Paradoxical Vasospasm During Ia Milrinone Infusion
American Journal of Respiratory and Critical Care MedicineAbstract Introduction Intra-arterial (IA) milrinone is used as a rescue therapy for refractory cerebral vasospasm. However, paradoxical hemodynamic worsening during continuous IA milrinone infusion has not been reported in the literature. We present a unique case of this phenomenon in a patient
J A Carrizosa +3 more
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