Results 91 to 100 of about 4,504 (203)

Wnt dependency confirmed through the utilization of Wnt pathway inhibitors: ETC159, C59.

All growth is expressed as percent viability respective to control (no drug). For all Wnt pathway inhibition assays, organoids were grown in minimal growth media (Panc129: ENRA, Panc193: ENRAS, Panc269: R, Panc271: NRA, Panc308: ENRA, Panc272: media ...
Peter J. Dempsey (18340392), Stacey M. Bagby (9602991), Hayley J. Hawkins (18340377), Wells A. Messersmith (7872122), Christopher H. Lieu (10431137), Betelehem W. Yacob (9602997), John J. Arcaroli (14931366), Monica E. Brown (18340380), Brandon R. Goldstein (18340383), Todd M. Pitts (9603003), Thomas Danhorn (689763), Andrew Goodspeed (11914527), Robert W. Lentz (18340389), Morgan Macbeth (18340386), Sarah J. Hartman (9602994), Alexis D. Leal (10431143)   +15 more
core   +1 more source

Evaluation of Pharmacokinetics of Prx Inhibitor from Rat Plasma Data Using HPLC-UV Method

, 2011
이 연구의 목적은 Prx I 저해제로 알려진 4-(4-(1H-pyrrol-1-yl)benzyl)-N-(3-acetylphenyl)piperidine-1-carboxamide (C59)를 쥐 혈장 중에서 정량하기 위한 HPLC 방법을 확립하고, 쥐에 C59를 정맥 주사 또는 경구 투여한 뒤 얻은 혈장 샘플을 분석하여 약물동태학적으로 평가하는 것이다. 쥐의 혈장에서 C59를 정량하기 위해 혈장 중의 C59와 내부표준물질을 추출액인 아세토니트릴로 한번에
최종민
core   +1 more source

Post-treatment malaria transmission in relation to mutations in the dhfr and dhps genes.

, 2013
IQR = interquartile range; Non-ACT = treatment with sulphadoxine-pyrimethamine (SP) alone or in combination with amodiaquine; ACT = treatment with SP and artesunate (3 days).¥Gametocyte densities were measured by Pfs25 QT-NASBA.*Mutations were determined
Patrick Sawa (374722), Sabah A. Omar (374721), Mayke J. A. M. Oesterholt (374720), Colin J. Sutherland (257150), Louis C. Gouagna (310392), Teun Bousema (79969), Christina Howitt (374723), Michael Alifrangis (79967), Robert W. Sauerwein (82233)   +8 more
core   +1 more source

Dampak Green Management Dan Tanggung Jawab Sosial Perusahaan Terhadap Citra Perusahaan C59 Bandung

, 2017
Tujuan Penelitian ini adalah untuk mengetahui variabel Green Management, Corpororate Social Responbilty, dan Citra Perusahaan serta mengetahui berapa besar pengaruhnya secara parsial pada perusahaan C59 Bandung Green Management dan Corpororate Social ...
Putra, Bayu Mandala
core  

Prevalence of common point mutations of alpha globin gene in Babol, Iran (2005-09)

مجله دانشگاه علوم پزشکی گرگان, 2012
Background and Objective: Alpha thalassemia is one of the most common hemoglobin disorders. Some combination of alpha globin gene mutations may cause HbH disease with severe anemia or intermediate thalassemia.
Akhavan-Niaki H (PhD), Pourtaghi M (MD), Firouzjahi AR (MD), Banihashemi A (BSc), Sedaghat S (MD)   +4 more
doaj  

Single-cell and immune-context integration identifies basement-membrane/metastasis signatures that sharpen bladder-cancer diagnosis and prognosis

Discover Oncology
Background Bladder cancer(BLCA) has a high recurrence rate and metastasis, and its process is closely related to basement membrane remodeling. we developed an interpretable prognostic model based on metastasis–basement membrane–related genes (MBRGs) to ...
Ji Chen, Xiaobing Liu, Rongyin Ren, Renzheng Yi, Xiongfeng Zhang, Chaoqun Xie, Xinyu Liu, Weibing Long   +7 more
doaj   +1 more source

Inhibition of PORCN Blocks Wnt Signaling to Attenuate Progression of Oral Carcinogenesis

Purpose: Oral squamous cell carcinoma (OSCC) is commonly preceded by potentially malignant lesions, referred to as oral dysplasia. We recently reported that oral dysplasia is associated with aberrant activation of the Wnt/beta-catenin pathway, due to ...
Criollo, Alfredo, Torres, Vicente A., Lobos-Gonzalez, Lorena, Reyes, Montserrat, Flores, Tania, Kretschmar, Catalina, Pena-Oyarzun, Daniel, Contreras, Pamela, Quest, Andrew F. G., Maturana-Ramirez, Andrea   +9 more
core   +1 more source

Differentiation of human pluripotent stem cells towards corneal limbal stem cells : Optimization of the differentiation supplement Wnt-C59

Background and aims: Limbal stem cells (LSCs) are irreplaceable in the renewal of the corneal epithelium (CE). If the balance of their microenvironment is disrupted, or if the limbal area is subjected to chemical or mechanical injury, the result may be ...
Laitala, Emilia
core  

Effect of boron-doping and electric field on CO₂ adsorption on C₆₀ fullerene. A DFT study. [PDF]

J Mol Model
Domínguez-Trujillo MDC, Dorazco-González A, Mandujano-Ramírez HJ, Flores-Chan JE, Sierra-Grajeda JMT, Martinez-Vargas S.   +5 more
europepmc   +1 more source

Poster Session C59: Neurodegeneration

Brain Pathology, 2000
openaire   +2 more sources