Results 51 to 60 of about 5,460 (176)
Association of MTHFR C677T and A1298C Gene Polymorphisms with Hypertension
International Journal of Health Sciences, 2012 To check for the association of genetic polymorphisms related to the methylenetetrahydrofolate reductase (MTHFR) gene namely C677T and A1298C with hypertension in Saudi affected subjects from Qassim region.Participants included 123 Saudi hypertensive cases (83 males and 40 females) in addition to 250 (142 males and 108 females) unrelated healthy ...
Abdullah, Alghasham +4 more
openaire +2 more sources
Overall survival according to MTHFR C677T genotype (P = 0.036).
, 2016 Overall survival according to MTHFR C677T genotype (P = 0.036).
Youngil Koh (3196416) +9 more
core +1 more source
Multi‐omics–driven precision medicine
iMeta, Volume 5, Issue 5, October 2026.Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li +20 more
wiley +1 more source
MTHFR C677T Polymorphisms in Non-syndromic Cleft Lip with or without Cleft Palate Patients [PDF]
Iranian Journal of Orthodontics, 2013 Background and aim: The etiology of CL/P is thought to be multifactorial with both genetic and environmental factors. Methylentetrahydrofolatereductuse (MTHFR), an important enzyme in folic acid metabolism with C677T polymorphism is one of the most ...
Shahrzad Tamasoki +4 more
doaj +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 9, September 2026.ABSTRACT Drug Combinations offer increased therapeutic efficacy and reduced toxicity compared with single agents. Understanding a drug combination's mechanisms of action (MoA) can provide important insights into therapeutic efficacy. The MoA of many FDA‐approved drugs, however, often remains unclear.
Rui‐Sheng Wang +5 more
wiley +1 more source
Distribution of MTHFR C677T in POAG Cases and Controls.
, 2014 Distribution of MTHFR C677T in POAG Cases and Controls.
Ritu Bhardwaj (603196) +8 more
core +1 more source
An eye on long‐duration spaceflight: Controversies, countermeasures and challenges
Experimental Physiology, Volume 111, Issue 9, Page 4004-4014, 1 September 2026.Abstract Space flight‐associated neuroocular syndrome (SANS) is a consequence of long‐duration space flight and is detected in two‐thirds of astronauts. In‐flight, this can cause a change in the refraction of the eyes, requiring graded hypermetropic ‘superfocus adjustable’ glasses, optic nerve head oedema and choroidal folds.
Vincent Wing Sum Ng +1 more
wiley +1 more source
Journal of Clinical Laboratory Analysis, Volume 40, Issue 16, August 2026.A laboratory‐customized, open‐sequence TaqMan‐MGB probe assay was developed for detecting CYP2C19*2 and CYP2C19*17 polymorphisms using dried blood spot‐derived DNA. The assay demonstrated allele‐specific discrimination, candidate LODs of 1.17 × 102 copies/μL for CYP2C19*2 and 0.94 × 103 copies/μL for CYP2C19*17, and repeatability with CVs below 10%. In
Yaqun Liu +7 more
wiley +1 more source
BMC Medical Genetics, 2012 Background 5,10-methylenetetrahydrofolate reductase (MTHFR) variants, C677T and A1298C, have been reported to be associated with decreased risk of acute lymphoblastic leukemia (ALL).
Wang Haigang +4 more
doaj +1 more source
Behavioural Neurology, 2021 Background. Methylenetetrahydrofolate reductase (MTHFR) C677T (rs1801133) gene polymorphisms are related to a growing risk of Alzheimer’s disease; however, whether this association applies to mild cognitive impairment (MCI) remains unclear. Objective. We
Jiahui Sun +6 more
doaj +1 more source