Results 61 to 70 of about 5,460 (176)

Genotype and allele frequency distribution of MTHFR C677T in β-TM patients and controls.

, 2016
Genotype and allele frequency distribution of MTHFR C677T in β-TM patients and controls.
Sherine M. Rizk (674089), Ilham Youssry (3169290), Amira A. Shaheen (3169287), Mai A. Abd-Elmawla (3169293)   +3 more
core   +1 more source

eNOS Uncoupling, Shear‐Stress Tolerance, and the Two‐Threshold Model of Post‐Exertional Malaise in Long COVID: A Mechanistic Hypothesis With Implications for Physiotherapy and Recovery Protocols

Microcirculation, Volume 33, Issue 6, August 2026.
ABSTRACT Objective To propose and make testable a mechanistic hypothesis for post‐exertional malaise (PEM) in a clinically distinct subset of Long COVID patients, in whom delayed exertional symptoms coexist with consistently normal macrovascular investigations.
Yiannis K. Karipidis, Konstantinos Y. Karipidis   +1 more
wiley   +1 more source

Distribution characteristics of MTHFR C677T gene polymorphism in Han nationality and women of childbearing age in 8 regions of Shaanxi province and a comparative analysis with other regions in China

Frontiers in Genetics
ObjectiveTo analyze the distribution characteristics of MTHFR C677T gene polymorphism in Shaanxi Province, thereby providing a genetic basis for folic acid supplementation strategies and the reduction of adverse pregnancy outcomes among reproductive-aged
Ting Chen, Fei Song, Jinyao Sun, Jing Yi, Wenbing Ma   +4 more
doaj   +1 more source

The influence of MTHFR genetic polymorphisms on methotrexate therapy in pediatric acute lymphoblastic leukemia

Open Life Sciences, 2021
MTHFR is a crucial enzyme in folate metabolism. This study aimed to determine the relationship between MTHFR genetic polymorphism and elimination and toxicities of methotrexate (MTX).
Shen Yaqing, Wang Zhujun, Zhou Fen, Jin Runming   +3 more
doaj   +1 more source

Arterial Hypertension and Methylenetetrahydrofolate Reductase C677T Gene Polymorphism

Kardiologiia, 2018
to determine the association of polymorphisms of C677T methylenetetrahydrofolate reductase (MTHFR) gene with essential arterial hypertension (EH) in the group of patients of Belarusian ethnicity.The clinical examination and molecular genetic study of the polymorphism C677T of MTHFR gene by polymerase chain reaction and restriction fragment length ...
O S, Pavlova, S E, Ogurtsova, M M, Liventseva, I Y, Korobko, A G, Mrochek   +4 more
openaire   +3 more sources

Neonates born at term with periventricular haemorrhagic infarction: Risk factors and clinical presentation

Developmental Medicine &Child Neurology, Volume 68, Issue 7, Page 1005-1012, July 2026.
This case series describes infants born near term with periventricular hemorrhagic infarction (PVHI), highlighting seizures as a common early symptom. Neonatal complications during delivery and pro‐thrombotic genetic mutations were slightly more common. MRI‐classified involvement was predominantly in the caudate vein territory.
Aleksandra Zaykova, Jeroen Dudink, Floris Groenendaal, Maarten H. Lequin, Manon J.N.L. Benders, Maria Luisa Tataranno, Elise Roze   +6 more
wiley   +1 more source

Overall and subgroup results of the association between MTHFR C677T polymorphism and NSCL/P.

, 2014
Overall and subgroup results of the association between MTHFR C677T polymorphism and NSCL/P.
Yue Zhang (30585), Baosen Zhou (102670), Mengmeng Zhao (514789), Li Shen (110858), Yangwu Ren (540810)   +4 more
core   +1 more source

Methotrexate Toxicity in a Patient With Renal Failure Despite a Normal Methotrexate Concentration: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Methotrexate (MTX) is a folate antagonist widely used as a disease‐modifying antirheumatic drug (DMARD) in rheumatoid arthritis (RA), as well as in several malignancies and autoimmune disorders. Although low‐dose MTX (5–20 mg/week) is generally considered safe, it has a narrow therapeutic index, and toxicity can occur even at therapeutic doses,
Fatemeh Afra, Mahshad Ghoddusi, Mahsa Mottahedi, Maryam Albaji, Samira Kafan, Roya Saedpanah, Amir Shokri, Elham Nazar   +7 more
wiley   +1 more source

Association between C677T variant of methylene tetrahydrofolate reductase and hypospadias risk in Algeria

The Turkish Journal of Pediatrics
Background. Hypospadias, a congenital condition characterized by the urethral opening being on the underside of the penis, has received limited attention in its association with the MTHFR C677T variant.
Rania Laouar, Djalila Chellat-Rezgoune, Meroua Horchi, Rayene Achou, Brahim Djoudi, Souhem Touabti, Yacine Benhizia, Karima Sifi   +7 more
doaj   +1 more source

Publication bias test (MTHFR C677T: T vs. C).

, 2014
Publication bias test (MTHFR C677T: T vs. C).
Fang Wu (267711), Yu-Tao Qin (525545), Yong Zhang (5893), Yan Su (342071), Ge-Ning Lu (525546), Ren-Sheng Wang (447514)   +5 more
core   +1 more source