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CA-125 in gynecological malignancies
European Journal of Cancer and Clinical Oncology, 1987CA-125 is an antigenic determinant that can be demonstrated in the majority of epithelial ovarian carcinomas. It can be measured in the serum with a radioimmunoassay by means of a monoclonal antibody. The tumor marker has a low specificity but high sensitivity for ovarian cancer, especially for serous cystadenocarcinoma.
W, Meier +4 more
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CA 125 in the management of endometriosis
European Journal of Obstetrics & Gynecology and Reproductive Biology, 1993CA 125 is expressed by eutopic and ectopic endometrium. In women with advanced endometriosis, plasma concentrations are increased towards the end of the luteal phase and during menstruation but not during the follicular and early luteal phases. In women without endometriosis, such cyclic changes of CA 125 in plasma are not observed.
P R, Koninckx +3 more
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CA-125 in Women with Endometriosis
Obstetrics and Gynecology Clinics of North America, 1989The serum CA-125 level is elevated in most women with endometriosis. Although tests are readily available to measure the marker, simple modifications of the present assays are required to improve and standardize the quality of the measurements. The serum test has low sensitivity and would not be appropriate for general screening purposes, but in ...
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CA 125 in peritoneal washings and fluid: Correlation with plasma CA 125 and peritoneal cytology
International Journal of Gynecology & Obstetrics, 1989Sixty-four women with ovarian cancer and 46 controls with benign gynecologic conditions underwent cytologic and CA 125 evaluations of peritoneal fluid or peritoneal washings at laparotomy. These parameters were correlated with preoperative disease status, intraoperative findings, and preoperative plasma CA 125 levels to determine their value in ...
P E, Schwartz +4 more
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Spontaneous uroperitoneum and elevated Ca-125
European Journal of Internal Medicine, 2008Spontaneous uroperitoneum occurs as a consequence of a traumatic rupture of the bladder (or ureters) leading to urinary ascites. Despite recognition of characteristic biochemical disturbances, the diagnosis remains problematic in cases without recognisable precipitating trauma.
Yu Xuan, Li, Ken, Vaux, Patrick, Coleman
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CA 125 in gynecological pathology — a review
European Journal of Obstetrics & Gynecology and Reproductive Biology, 1993The original CA 125 serum tumor marker test is a homologous double-determinant (OC 125 monoclonal antibody based) assay for the quantification of tumor associated mucin-like CA 125 molecules present in the serum. Commercial kits, now supplied by various manufacturers (and in different versions, e.g.
P, Kenemans +3 more
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CA 125 in Human Milk and Serum
Gynecologic and Obstetric Investigation, 2010CA 125 serum concentrations drawn immediately following delivery exceeded 35 U/ml in all cases (median 276 U/ml). One week post partum elevations of CA 125 were still found, but the median level decreased to 45 U/ml. Six weeks after parturition no positivity was detected in the serum (median 12 U/ml).
L C, Fuith, G, Daxenbichler, C, Marth
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CA 125 levels in abruptio placentae
American Journal of Obstetrics and Gynecology, 1991The diagnosis of abruptio placentae is frequently difficult despite ultrasonography; additional diagnostic parameters would be useful. Maternal serum CA 125, which is believed to derive from the decidua, is elevated in the first trimester and immediately after delivery when placental separation occurs, possibly because of decidual disruption.
B R, Witt +4 more
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CA 125 in the diagnosis of pelvic masses
European Journal of Cancer and Clinical Oncology, 1989CA 125 was measured preoperatively in 184 female patients presenting with pelvic masses. Ovarian tumors were diagnosed in 151 cases (91 carcinomas, eight borderline, 52 benign) and non-ovarian tumors in 33 (19 malignant, 14 benign). The sensitivity of CA 125 in identifying the malignant and borderline ovarian tumors was 86%, the specificity 78%; and ...
Mogensen, O; id_orcid 0000-0001-7655-9909 +2 more
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