Results 171 to 180 of about 936,523 (298)

Outcomes and Prognostic Factors in Hepatopancreatoduodenectomy. [PDF]

Yonsei Med J
Choi GW, Subasinghe D, Seo Y, Lee I, Han Y, Chae YS, Yun WG, Cho YJ, Jung HS, Kwon W, Jang JY, Park JS.   +11 more
europepmc   +1 more source

Comparison of the concentration of tumor markers carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA 19-9) with pathohistological diagnosis

Tumorski biljezi, poput karcinoembrionalnog antigena (CEA) i karbohidratnog antigena 19-9 (CA 19-9), često se koriste u dijagnostici i praćenju pacijenata s karcinomom debelog crijeva.
Perković, Petra
core  

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Irreversible electroporation combined with immunotherapy versus irreversible electroporation alone for locally advanced pancreatic cancer: a systematic review and meta-analysis. [PDF]

Einstein (Sao Paulo)
Mariussi M, Lima LCO, Ruelas MG, Ohannesian VA, Murad B, Oliveira GS, Schmitt LG, Torri GB, Altmayer S, Falsarella PM, Usón Junior PLS, Garcia RG.   +11 more
europepmc   +1 more source

Time‐Multiplexed Organic Electrochemical Transistor for Saliva‐Based Rapid Detection of Viral Proteins

Advanced Science, EarlyView.
A time‐multiplexed nanobody‐functionalized organic electrochemical transistor enables rapid and sensitive detection of three respiratory viral proteins from saliva. Sequentially addressed multi‐gate electrodes on a shared channel achieve around 1 fm detection within 15 min without sample preprocessing. Clinical validation demonstrates high specificity,
Tianrui Chang, Yuxiang Ren, Shofarul Wustoni, Atheer Alqatari, Adel Hama, Yazhou Wang, Long Chen, Jessica Parrado Agudelo, Luca Salvigni, Keying Guo, Ashraf Dada, Stefan T. Arold, Raik Grünberg, Sahika Inal   +13 more
wiley   +1 more source

The Varied Presentation of Appendiceal Mucinous Neoplasms: A Rural Case Series. [PDF]

Cureus
Vu D, Pajtak R, Strauss P.
europepmc   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Initial Site of Metastasis Influences Prognosis in Pancreatic Ductal Adenocarcinoma. [PDF]

Cancer Med
Mancheski E, Baek D, Bowne W, Lavu H, Yeo CJ, Nevler A.   +5 more
europepmc   +1 more source

Association of Circulating Carbohydrate Antigen 19-9 Level with Type 2 Diabetic Kidney Disease in Chinese Adults: A Cross-Sectional Study

Pijun Yan,1– 5 Jia Li,1– 5 Yi Zhang,1– 5 Xiaofang Dan,1– 5 Xian Wu,1– 5 Xing Zhang,1– 5 Yuxia Yang,1– 5 Xiping Chen,6 Shengxi Li,6 Pan Chen,1– 5 Qin Wan,1– 5 Yong Xu1– 5 1Department of Endocrinology and Metabolism, the Affiliated Hospital of Southwest ...
Dan X, Wan Q, Li J, Yang Y, Chen P, Li S, Yan P, Zhang Y, Zhang X, Chen X, Wu X, Xu Y   +11 more
core  

O‐GlcNAcylated TAP1 Impairs Antigen Presentation and Promotes Immune Evasion in Bladder Cancer

Advanced Science, EarlyView.
This article unveils a critical mechanism of immune evasion in bladder cancer, which the O‐GlcNAc modification of TAP1 disrupts antigen presentation. This modification triggers HLA‐A degradation, shielding tumor cells from CD8+ T cell attack. The findings highlight targeting this pathway as a promising therapeutic avenue to sensitize tumors to ...
Jinpeng Wu, Xueting Ren, Zhen Zhai, Lu Wang, Liang Liang, Zengqi Tan, Jiazhen Zhao, Yuxuan Han, Yuhan Li, Feng Guan, Xiang Li   +10 more
wiley   +1 more source