Results 251 to 260 of about 1,191,068 (306)

Design of Safe and Efficient Adenine Base Editors via Protein Language Model Screening for Osteoarthritis Treatment

Advanced Science, EarlyView.
ABSTRACT Base editors enable precise genome modification and have emerged as a promising therapeutic approach for correcting diseases caused by single‐nucleotide variants. While the current efficient version of adenine base editors (ABEs), such as ABE8e, exhibits exceptional efficiency for A‐to‐G conversions, their clinical translation is hindered by ...
Jiawei Yao, Dalin Chen, Ziyi Zhang, Jingxuan Ren, Chengcheng Zhao, Shengfang Wang, Mengyu Shang, Dawei Jiang, Yinuo Li, Su'an Tang, Kai Li, Xiaohui Zhang, Xiaogang Wang   +12 more
wiley   +1 more source

A Rare and Aggressive Klatskin Tumor Revealed by Magnetic Resonance Cholangiopancreatography (MRCP): A Diagnostic Case Report. [PDF]

Cureus
Flores García EA, Lugo Rodríguez AD, Navarro Morales J, Rodríguez Murua JI, Maciel JF, Favela Ramos JA, Vazquez Tovar JA.   +6 more
europepmc   +1 more source

Preoperative prognostic model combining tumor burden score and tumor markers to predict long-term outcomes following hepatectomy for intrahepatic cholangiocarcinoma: a multi-institutional analysis. [PDF]

Front Oncol
Fu J, Huang T, Lin Q, Li J, Bi X, Wang J, Li F, Wang J, Wang K, Lou J, Cheng S, Zeng Y.   +11 more
europepmc   +1 more source

Detection of Prostate Carcinoma in an Asymptomatic Individual Initiated by an Immunological Biopsy-A Case Report. [PDF]

Oncol Res
Burg S, Grust ALC.
europepmc   +1 more source

Preoperative gastric cancer immune prognostic score (GCIPS) as a novel biomarker for predicting survival in gastric cancer patients after radical resection: A retrospective cohort study. [PDF]

Medicine (Baltimore)
Hu X, Li J, Zhang S.
europepmc   +1 more source

Improved preoperative clinical staging system for intrahepatic cholangiocarcinoma using the ABC factors: a retrospective study. [PDF]

Front Oncol
Huang Y, Ye W, Huang J, Xu L, Zhang Y, Xing R, Zhang Z.   +6 more
europepmc   +1 more source

Radiofrequency Ablation and Chemotherapy vs Chemotherapy Only in Locally Advanced Pancreatic Cancer: The PELICAN Randomized Clinical Trial.

JAMA Netw Open
Seelen LWF, Brada LJH, Walma MS, Rombouts SJE, Braat MN, Bollen TL, Borel Rinkes IH, Bruijnen RCG, Busch OR, Cirkel GA, Daamen LA, Daams F, van Dam RM, van Delden OM, Derksen WJM, Festen S, Groothuis K, Hagendoorn J, de Hingh IHJT, D'Hondt M, Liem MSL, van Lienden KP, Los M, de Meijer VE, Mekenkamp LJM, Nijkamp MW, Nio CY, Pando E, Patijn GA, Polée MB, Te Riele WW, Roeyen G, Stommel MWJ, de Vos-Geelen J, de Vries JJ, Wessels FJ, Wilmink JW, van de Ven PM, Besselink MG, van Santvoort HC, Molenaar IQ, Dutch Pancreatic Cancer Group.   +41 more
europepmc   +1 more source

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A case of bronchogenic cyst with high production of antigen CA 19–9

Cancer, 1989
A 35-year-old man was hospitalized with complaints of retrosternal pain and high fever. A chest radiograph showed a large round mass in the mediastinum. Of the several tumor markers in the serum tested, only CA 19-9 was elevated. Thoracotomy revealed a cystic mass with purulent hemorrhagic materials.
A, Okubo, S, Sone, F, Ogushi, T, Ogura, T, Uyama, Y, Monden, K, Ii   +6 more
openaire   +2 more sources

Carbohydrate Antigenic Determinant (CA 19–9) and Other Tumor Markers in Gastrointestinal Malignancies

Digestion, 1985
The serum carbohydrate antigenic determinant (CA 19-9) was assayed in patients with various diseases, and it provides excellent sensitivity for adenocarcinoma of the pancreas (25/27, 93%), while only 4% (2/54) of the patients with benign diseases and none of the 40 healthy subjects showed elevated CA 19-9 concentrations over 37 units/ml as upper normal
T, Yoshikawa, K, Nishida, M, Tanigawa, K, Fukumoto, M, Kondo   +4 more
openaire   +2 more sources