Results 21 to 30 of about 6,016 (195)

Serum level of carbohydrate antigen 15-3 in patients with interstitial lung diseases and its correlation with pulmonary function and high-resolution computed tomography

The Egyptian Journal of Bronchology, 2019
Background Carbohydrate antigen 15-3 (CA15-3) is a central protein core of mucin-1, a high-molecular-weight glycoprotein, found in alveolar and extrapulmonary epithelial cells that increases in interstitial lung disease.
Randa Salah El-Din Mohamed, Mahmoud Mohammed El-Batanouny, Neveen Mahmoud Amin, Rasha Abdel Razek Mahmoud, Doaa A. A. Abd-Elhalim   +4 more
doaj   +1 more source

Re-evaluation of HER2 status in metastatic breast cancer and tumor-marker guided therapy with vinorelbine and trastuzumab [PDF]

, 2005
Background: HER2 is overexpressed in 20 - 30% of breast cancers. Compared to chemotherapy alone, chemotherapy with trastuzumab improves clinical outcome in patients with HER2- positive metastatic breast cancer ( MBC). In general, HER2 status in a primary
Heinemann, Volker, Lässig, D., Stemmler, H. J., Stieber, P.   +3 more
core   +1 more source

Independent prognostic impact of preoperative serum carcinoembryonic antigen and cancer antigen 15-3 levels for early breast cancer subtypes

World Journal of Surgical Oncology, 2018
Background Although the prognosis for operable breast cancers is reportedly worse if serum carcinoembryonic antigen (CEA) and cancer antigen 15-3 (CA15-3) levels are above normal, the usefulness of this prognosis is limited due to the low sensitivity and
Michiko Imamura, Takashi Morimoto, Takashi Nomura, Shintaro Michishita, Arisa Nishimukai, Tomoko Higuchi, Yukie Fujimoto, Yoshimasa Miyagawa, Ayako Kira, Keiko Murase, Kazuhiro Araki, Yuichi Takatsuka, Koshi Oh, Yoshikazu Masai, Kouhei Akazawa, Yasuo Miyoshi   +15 more
doaj   +1 more source

Oral contraceptive use and salivary C-erbB-2, CEA and CA15-3 in healthy women : a case-control study [PDF]

, 2011
Objectives: Oral contraceptives (OCP) are highly effective, safe and widely used. Higher exposure to endogenous and exogenous estrogens is generally thought to increase the risk of breast cancer. Therefore, this study was conducted to determine if oral
Abdollahzadeh, Shermin, Mortazavi, Hamed, Vahedi, Mohammad, Vaziri, Pejman Bakianian   +3 more
core   +1 more source

Analysis of tumor markers in pleural effusion and serum to verify the correlations between serum tumor markers and tumor size, TNM stage of lung adenocarcinoma

Cancer Medicine, 2020
Background The study of tumor markers (TM) in pleural effusion (PE) was not extensive. Methods TM in PE and serum were analyzed to determine whether TM was expressed in intrathoracic and extrathoracic tissues.
Zhongqing Chen, Ying Wang, Min Fang
doaj   +1 more source

Elevated Levels of Serum Tumor Markers CEA and CA15-3 Are Prognostic Parameters for Different Molecular Subtypes of Breast Cancer.

PLoS ONE, 2015
Background & aimsThe utility of measuring carcinoembryonic antigen(CEA) and cancer antigen 15-3 (CA15-3) levels in patients with breast cancer remains controversial. The present study aims to investigate the prognostic value of preoperative serum CEA and
Yingbo Shao, Xianfu Sun, Yaning He, Chaojun Liu, Hui Liu   +4 more
doaj   +1 more source

Combination Twist1 and CA15-3 in axillary lymph nodes for breast cancer prognosis. [PDF]

Mol Med Rep, 2017
Twist1 overexpression is involved in epithelial‑mesenchymal transition resulting in migration and metastasis of breast cancer. Carcinoma antigen 15‑3 (CA15‑3) is widely used to monitor the prognosis for patients after treatment. However, the significance of Twist1 in axillary lymph nodes (ALN) and CA15‑3 for co‑examination for survival rates remains to
Jiang X, Guo D, Li W, Yu T, Zhou J, Gong J.   +5 more
europepmc   +4 more sources

Primary cutaneous signet ring cell carcinoma expressing cytokeratin 20 immunoreactivity [PDF]

, 2006
Primary cutaneous signet ring cell carcinoma (PCSRCC) is a very unusual but distinctive clinicopathologic entity that can simulate metastatic adenocarcinomas.
59244, 59245, 59246, 59247, 59248, ANSAI, Shinichi, KIYOHARA, Takahiro, KOURABA, Sachio, KUMAKIRI, Masanobu, TOKURIKI, Atsushi   +9 more
core   +1 more source

Rapid Breast Cancer Disease Progression Following Cyclin Dependent Kinase 4 and 6 Inhibitor Discontinuation. [PDF]

, 2017
Background: CDK 4 and 6 inhibitors (CDK4/6i), which arrest unregulated cancer cell proliferation, show clinical efficacy in breast cancer. Unexpectedly, a patient treated on a CDK4/6i-based trial, as first-line therapy in metastatic breast cancer ...
Abouharb, Sausan, Bashour, Sami I, Brown, Powel H, Doostan, Iman, Ibrahim, Nuhad K, Karuturi, Meghan, Keyomarsi, Khandan, Koenig, Kimberly B, Litton, Jennifer K, Moulder-Thompson, Stacy L, Tripathy, Debasish, Ueno, Naoto T, Valero, Vicente   +12 more
core   +2 more sources

Tumor burden monitoring using cell-free tumor DNA could be limited by tumor heterogeneity in advanced breast cancer and should be evaluated together with radiographic imaging [PDF]

, 2017
BACKGROUND: Accurate measurement of tumor burden in breast cancer disease is essential to improve the clinical management of patients. In this study, we evaluate whether the fluctuations in the fraction of PIK3CA mutant allele correlates with tumor ...
Atocha Romero, Daniel Acosta-Eyzaguirre, Eduardo Díaz-Rubio, Fernando Moreno, José Angel García-Saenz, Julián Sanz, Marion Laig, Marta García-Esquinas, Miguel Barquín, Myriam Montes, Patricia Ayllón, Trinidad Caldes, Vanesa Garcia-Barberan   +12 more
core   +1 more source