Results 171 to 180 of about 618,626 (288)

The CAGE Framework (Calcium-Gated Excitability): From Single Neurotransmitters to Calcium States in the Tumor Microenvironment. [PDF]

Int J Mol Sci
Rudy LM, Godlewski MM.
europepmc   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

An atypical EF-hand domain containing resistance protein SRC4 boosts plant immunity in a calcium-enhanced manner. [PDF]

Plant J
Zhou Z, Miao D, Zhao J, Zhou Y, Yan T, Niu N, Bao Z, Lv F, Liu L, Xu N, Yan F, Liu J, Wuriyanghan H.   +12 more
europepmc   +1 more source

SOD1 PREVENTS MOTOR NEURON DEATH INDUCED BY THE CYCAD NEUROTOXIN BETA-METHYLAMINO-L-ALANINE BY MODULATING PLASMA MEMBRANE TARGETS INVOLVED IN INTRACELLULAR Ca2+ HOMEOSTASIS

, 2018
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the loss of motor neurons. Although the incoming knowledge on the genetic aspects of the disease, the pathogenesis remains unknown.
Pannaccione A, De Flora A, Annunziato L, Boscia F, Secondo A, Petrozziello T, Tedeschi V, Bruzzone S   +7 more
core  

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Utero-placental calcium and magnesium ion channels: A systematic review of obstetric implications of their alterations. [PDF]

Channels (Austin)
Ndinganire G, Niyomugabo AP, Owu DU, Olubiyi MV, Ikwuka DC, Niyodusenga A, Adeniyi MJ, Walle M, Okeke OC, Feyitimi AA, Eze ED, Ime AU, Ani EJ, Jimoh A, Umar AH, Haile DW, Alagbonsi AI, Onaadepo O.   +17 more
europepmc   +1 more source

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source

Complexation of Divalent Metals by Natural Furoquinoline Alkaloids: An Electrospray Mass Spectrometry and DFT Study. [PDF]

Rapid Commun Mass Spectrom
Valdez MB, Palermo JA, D'Jonsiles F, Cabrera GM, Siless GE.   +4 more
europepmc   +1 more source

Flexoelectricity in Photoconversion: Fundamentals, Materials, and Outlooks

Advanced Science, EarlyView.
Mechanical bending of a flexible cantilever induces a strain gradient in the photoactive material. The resulting flexoelectric field couples with photovoltaic and photoconductive effects, modulating charge generation, separation, and collection. A comparative analysis of oxide perovskites, halide perovskites, and two‐dimensional materials is presented,
Xiang Huang, Feng Li, Rongkun Zheng
wiley   +1 more source

Organelle-specific crosstalk between calcium and redox signaling in pancreatic β-cells in physiology and type 2 diabetes. [PDF]

Front Netw Physiol
Camara LRP, Vilas-Boas EA.
europepmc   +1 more source