Results 181 to 190 of about 667,052 (292)

From agricultural waste to functional gels: Mulberry pomace-derived carboxymethyl cellulose synergistically enhances calcium-mediated peanut protein isolate gelation. [PDF]

Food Chem X
Ge Y, Hu D, Sun Y, Tong Y, Shi H, Wang C.   +5 more
europepmc   +1 more source

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Right Place, Right Function: The Contribution of Subcellular Localization to the Physiological Impact of TRPM2 Channels. [PDF]

Life (Basel)
Hasselsweiller A, Nguyen BC, Soussi M, Gkika D.   +3 more
europepmc   +1 more source

Polymorphic Superparaelectric Engineering Boosting Energy Storage Capacity in BaTiO3‐Based Ceramics

Advanced Science, EarlyView.
Herein, Ca2+ incorporation promotes the coexistence of CaTiO3‐/BaTiO3‐derived paraferroelectric states, stabilizing cubic‐orthorhombic‐tetragonal polymorphic superparaelectric phases. This minimizes polarization energy barriers, facilitating full polarization saturation without compromising efficiency.
Pan Liu, Xiang Ren, Jin Qian, Haihua Huang, Peng Li, Peng Fu, Jigong Hao, Huarong Zeng, Wei Li, Zhenxiang Cheng   +9 more
wiley   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

CalDyn: an advanced high-throughput automated algorithm for monitoring intracellular calcium dynamics and electrophysiological signals in patient-derived cells. [PDF]

Brief Bioinform
Sleiman Y, El Achkar G, Colombani S, Estève E, Reisqs JB, Kervella M, Goual L, Bounasri E, Ferreira MJ, Cupelli M, Torrente AG, Thireau J, Costa PF, Boutjdir M, Lacampagne A, Muchir A, Seyer P, Delanoë-Ayari H, Meli AC.   +18 more
europepmc   +1 more source

Low‐Intensity Focused Ultrasound Enables Temporal Modulation of Human Midbrain Organoid Differentiation

Advanced Science, EarlyView.
In this study, we demonstrate that low‐intensity ultrasound stimulation enables temporal modulation of midbrain organoid differentiation using a modular multi‐well stimulation platform. In particular, we show that ultrasound promotes the proliferation of dopaminergic progenitor cells.
Jinseong Jeong, Yehhyun Jo, Youngsun Lee, Eunyoung Jang, Yeonji Jeong, Won Do Heo, Jennifer H. Shin, Mi‐Ok Lee, Hyunjoo J. Lee   +8 more
wiley   +1 more source

Cryo-EM and NMR Reveal a Membrane-Gated Doc2B-Munc13-1 Complex and a Helical Doc2B-SNARE-Binding Interface. [PDF]

Adv Sci (Weinh)
Rastegar CT, Powell J, Wosztyl A, David G, Jaczynska K, Bai XC, Han Y, Chen Z, Rizo J.   +8 more
europepmc   +1 more source

Single‐Cell Dissection of Microglial Dysfunction in Diabetes‐Associated Neurodegenerative Vulnerability

Advanced Science, EarlyView.
Using single‐cell transcriptomic and epigenomic profiling, researchers mapped microglial dysfunction across the lifespan of db/db mice. The authors uncovered a nonlinear microglial remodeling featuring early inflammatory priming, a mid‐stage transcriptional inflection, and late dysfunction.
Jizhou Zhang, Tsz Kwan Yau, Joyce Tse, Tsz Ho Li, Dongjie Hu, Yong Juan Zhao, Ting‐Fung Chan   +6 more
wiley   +1 more source

From Signal to Memory: A Proposed Adaptive Hierarchy Linking Autism-Associated Genes to Sensory Homeostasis. [PDF]

Genes (Basel)
Gargus JJ.
europepmc   +1 more source