Results 201 to 210 of about 438,683 (248)

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

open access: yesAdvanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao   +10 more
wiley   +1 more source

Carboxyphenolate Coordination Frameworks for High‐Voltage Calcium Storage

open access: yesAdvanced Science, EarlyView.
A hexaanionic carboxyphenolate coordination framework, Ca2‐M‐THBPD (M = Mg, Ca, Ba), exhibits ligand‐centered enolate‐quinonoid redox activity enabling tunable, high‐voltage Ca2+ storage (3.5 V vs Ca2+/Ca) modulated by spectator cations. The amorphous structure accommodates reversible divalent‐ion insertion, contributing to enhanced cycling stability ...
Vasudeva Rao Bakuru   +12 more
wiley   +1 more source

The Ca<sup>2+</sup>-NO-ROS Crosstalk Induced by Arachidonic Acid in Human Lung Fibroblasts: Implications for Pulmonary Fibrosis. [PDF]

open access: yesInt J Mol Sci
Esmeralda Sánchez-Pluma K   +8 more
europepmc   +1 more source

A New Customizable Surfactant LLPS Strategy for Sustainable and Highly Efficient Radioactive Metal Ion Separation

open access: yesAdvanced Science, EarlyView.
A diluent‐free, customizable liquid–liquid phase separation (LLPS) platform enables highly efficient radioactive metal ion extraction and stripping. By encapsulating hydrophobic extractants into an ionic surfactant‐rich condensed phase, this LLPS system leverages synergistic electrostatic and coordination interactions.
Ruihan Yan   +7 more
wiley   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

open access: yesAdvanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao   +25 more
wiley   +1 more source

Unraveling new functions of the Ca2+ sensor STIM1 in cell signaling. [PDF]

open access: yesBiochem Soc Trans
Sanchez-Lopez I   +4 more
europepmc   +1 more source

Furoxan derivatives with antimalarial activity that disrupt P. falciparum endoplasmic reticulum calcium homeostasis. [PDF]

open access: yesInt J Parasitol Drugs Drug Resist
da Costa Clementino L   +9 more
europepmc   +1 more source

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