Results 241 to 250 of about 10,961,826 (306)

Cergutuzumab Amunaleukin in Combination with Atezolizumab in Patients with Carcinoembryonic Antigen-Positive Advanced/Metastatic Solid Tumors. [PDF]

Clin Cancer Res
Melero I, Tabernero J, Steeghs N, Robbrecht DGJ, Peters S, Rizvi NA, O'Reilly EM, Calvo E, Eefsen RL, Leighl N, Cervantes A, Hafez N, Habigt C, Andersson E, Dejardin D, Rossmann E, Martinez Quetglas I, Babitzki G, Duarte J, Adessi C, Boetsch C, Evers S, Charo J, Teichgräber V, Lassen U.   +24 more
europepmc   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Association between early arterial pH, base excess and lactate and 24-h mortality and neurological outcomes after cardiac arrest and cardiopulmonary resuscitation: a translational study. [PDF]

Resusc Plus
Callegari F, De Giorgio D, Merigo G, Cerrato M, Tinelli O, Magliocca A, Zanier ER, Ristagno G, Fumagalli F.   +8 more
europepmc   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Incidence and risk factors of contrast-associated acute kidney injury in patients hospitalised after contrast-enhanced computed tomography in the emergency department. [PDF]

Int J Emerg Med
Lecomte E, Vaittinada Ayar P, Vilgrain V, Vaittinada Ayar P.   +3 more
europepmc   +1 more source

Opioid consumption during hospitalisation among robotic-assisted, computer-assisted, and manual total hip arthroplasty: a retrospective cohort study. [PDF]

BJA Open
Giannakis P, Rowe JE, Ren R, Reisinger L, Illescas A, Sideris A, Cozowicz C, Wang J, Zhuang ST, Covin SE, Maalouf D, Liu J, Poultsides L, Memtsoudis SG, Marx RG, Poeran J, Della Valle AG.   +16 more
europepmc   +1 more source

Diagnostic Value of CA-125 and Other Tumor Biomarkers in Children with Suspected Malignancy: A Retrospective Cohort Study. [PDF]

Diagnostics (Basel)
Çalışkan Kamış Ş, Çil M, Yağcı B.   +2 more
europepmc   +1 more source

Prevalence, risk factors and mortality associated with colonic atresia: a population-based case-control study. [PDF]

Pediatr Surg Int
Kankaristo R, Helenius I, Heiskanen S, Syvänen J, Kemppainen T, Löyttyniemi E, Gissler M, Raitio A.   +7 more
europepmc   +1 more source