Results 81 to 90 of about 13,845,908 (273)

CA 19‐9 and carcinoembryonic antigen in pancreatic cancer diagnosis

, 1986
CA 19-9 (Centocor, Malvern, PA) and carcinoembryonic antigen (CEA), two recently developed immunoradiometric assays utilizing monoclonal antibodies, were evaluated in the sera of 139 subjects in order to assay their individual and combined value in ...
FABRIS C., PEDRAZZOLI, SERGIO, BURLINA A., PICCOLI, ANTONIO, PEROBELLI L., PLEBANI, MARIO, DEL FAVERO G., NACCARATO R., PANUCCI A., BACCAGLINI U.   +9 more
core   +1 more source

Elevated serum CA 19-9 levels in patients with pulmonary nontuberculous mycobacterial disease

Brazilian Journal of Infectious Diseases, 2016
Increased serum CA 19-9 levels in patients with nonmalignant diseases have been investigated in previous reports. This study evaluates the clinical significance of serum CA 19-9 elevation in pulmonary nontuberculous mycobacterial disease and pulmonary ...
Ji Young Hong, Sun Hee Jang, Song Yee Kim, Kyung Soo Chung, Joo Han Song, Moo Suk Park, Young Sam Kim, Se Kyu Kim, Joon Chang, Young Ae Kang   +9 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

The Value of Serum CA 19-9 in Predicting Cholangiocarcinomas in Patients with Primary Sclerosing Cholangitis

, 2005
CA 19-9 has been used with questionable accuracy to aid diagnosis of cholangiocarcinoma complicating primary sclerosing cholangitis. We aimed to characterize the test properties of CA 19-9 and of a change in CA 19-9 over time in predicting ...
Angulo, Paul, Gores, Gregory, Levy, Cynthia, Lindor, Keith, Lymp, James, Larusso, Nicholas   +5 more
core   +1 more source

Akciğer Kanserinin Tümör Belirteçleri ile Değerlendirilmesi: CEA, CA 19-9 ve CA 125

, 2021
Aim: Lung cancer (LC) is a common and mortal malignancy. Tumor biomarkers are measurable biochemicals associated with cancer cells. Tumor markers cannot diagnose cancer; instead, they can be used as laboratory tests to support the diagnosis.
Muhammed EMİN, Aydın, Suphi, Emin, Muhammet, Aydın Balcı, Suphi AYDIN, Balcı, Aydın, Aydın BALCI, Suphi Aydın   +7 more
core   +2 more sources

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Kalp yetersizliği olan hastalarda CA 125, CA 19-9, CA 15-3, CEA ve AFP'nin değerlendirilmesi

, 2006
Kronik kalp yetersizliği olan hastalarda CA 125, CA 19-9, CA 15-3, CEA, AFP'nin değerlendirilmesi Amaç: Kalp yetersizliği (KY) olan hastalarda serumda tümör markerlarının düzeylerinin arttığı ileri sürülmektedir.
Tekin, Gülaçan Özgün
core   +1 more source

Acute Cholecystitis with Significantly Elevated Levels of Serum Carbohydrate Antigen 19-9

Case Reports in Gastroenterology, 2016
Serum carbohydrate antigen 19-9 (CA 19-9), a marker of malignant tumors, is generally slightly elevated in benign conditions. We report a case of acute cholecystitis with a significantly elevated level of serum CA 19-9 based on positron emission ...
Shuji Akimoto, Masataka Banshodani, Masahiro Nishihara, Junko Nambu, Yasuo Kawaguchi, Fumio Shimamoto, Kiyohiko Dohi, Keizo Sugino, Hideki Ohdan   +8 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source