Results 71 to 80 of about 8,070,232 (284)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
53BP1 expression is a modifier of the prognostic value of lymph node ratio and CA 19–9 in pancreatic adenocarcinoma [PDF]
, 2013 BACKGROUND: 53BP1 binds to the tumor suppressor p53 and has a key role in DNA damage response and repair. Low 53BP1 expression has been associated with decreased survival in breast cancer and has been shown to interact with several prognostic factors in ...
Anuradha Bapsi Chakravarthy +8 more
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
The International Journal of Biological Markers, 1987 Levels of CA 19-9 in the serum and duodenal juice of nine patients with pancreatic adenocarcinoma (PC), ten patients with chronic calcifying pancreatitis (CCP) and ten healthy volunteers (C) were determined by immunoassay.
Gianfranco Tappero, Paolo Piantino
doaj +1 more source
Biochemical markers in cancer of the ovary : a review [PDF]
, 1990 The ideal tumour marker would be one which is detectable before obvious clinical involvement. A number of biochemical markers have been used to diagnose carcinoma of the ovary.
Cauchi, Maurice N.
core
Two Lane Traffic Simulations using Cellular Automata
, 1995 We examine a simple two lane cellular automaton based upon the single lane CA introduced by Nagel and Schreckenberg. We point out important parameters defining the shape of the fundamental diagram.
A. Latour +26 more
core +5 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The Reliability of Highly Elevated CA 19‐9 Levels [PDF]
Disease Markers, 1993 CA 19‐9 is used as a tumour marker of the upper gastrointestinal tract. However, extremely elevated CA 19‐9 levels are found also in patients with benign diseases. Cholestasis was present in 97.1 % of patients with high elevated CA 19‐9, independent of their primary disease.
B R, Osswald, F E, Klee, S, Wysocki
openaire +2 more sources
The multi-faceted Type II-L supernova 2014G from pre-maximum to nebular phase [PDF]
, 2016 We present multi-band ultraviolet, optical, and near-infrared photometry, along with visual-wavelength spectroscopy, of supernova (SN) 2014G in the nearby galaxy NGC 3448 (25 Mpc). The early-phase spectra show strong emission lines of the high ionisation
Arcavi, I. +20 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source