Results 61 to 70 of about 1,191,145 (307)

Biochemical markers in cancer of the ovary : a review [PDF]

, 1990
The ideal tumour marker would be one which is detectable before obvious clinical involvement. A number of biochemical markers have been used to diagnose carcinoma of the ovary.
Cauchi, Maurice N.
core  

Alternative antibody for the detection of CA19-9 antigen: a European multicenter study for the evaluation of the analytical and clinical performance of the Access (R) GI Monitor assay on the UniCel (R) Dxl 800 Immunoassay System [PDF]

, 2008
Background: Gastrointestinal cancer antigen CA19-9 is known as a valuable marker for the management of patients with pancreatic cancer. Methods: The analytical and clinical performance of the Access(R) GI Monitor assay (Beckman Coulter) was evaluated on ...
Barone D, Bekaii-Saab TS, Dittadi R, Gogas H, Heinemann V, Ishii H, Jiang XT, Magnani JL, Micke O, Molina R, Reiter W, Reiter W, Safi F, Steinberg W, Tempero MA, Wang WS   +15 more
core   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Etiology of Severe Non-malaria Febrile Illness in Northern Tanzania: A Prospective Cohort Study. [PDF]

, 2013
The syndrome of fever is a commonly presenting complaint among persons seeking healthcare in low-resource areas, yet the public health community has not approached fever in a comprehensive manner.
AJ Bouley, Anne B. Morrissey, B Nadjm, B Nadjm, B Pastorino, BM Greenwood, CA Petti, Charles Muiruri, CIR Chandler, CJ Murray, CJ Murray, DC Clifton, DR Feikin, EA Reddy, Eng Eong Ooi, Grace D. Kinabo, H Reyburn, HM Biggs, JA Berkley, JA Crump, JA Crump, JA Crump, JA Crump, John A. Bartlett, John A. Crump, JT Hertz, K Baltzell, LE Scott, LK Archibald, M Amexo, M Prabhu, Mathieu Picardeau, MD Bajani, MK Mayhood, MM Levine, N Scaramozzino, OS Levine, PA Connolly, PL Petit, R Lozano, Renee L. Galloway, Robert F. Massung, Robyn A. Stoddard, SI Hay, SJ Olsen, SL Brown, SM Graham, SM Lofgren, TJ O'Dempsey, Venance P. Maro, Wilbrod Saganda, William L. Nicholson, YL Lai   +52 more
core   +11 more sources

High Carbohydrate 19-9 Antigen Serum Levels in Patients with Nonmelanoma Skin Cancer and Primary Occult Cancer

Biomedicines, 2020
Background: Non-melanoma skin cancers (NMSC), despite having a favourable prognosis, present an increased risk of occult malignancies. The aim of this study was the evaluation of the usefulness of the mucinous marker carbohydrate 19-9 antigen (CA 19-9 ...
Giulia Malaguarnera, Saverio Latteri, Roberto Madeddu, Vito Emanuele Catania, Gaetano Bertino, Rosario Emanuele Perrotta, Francesco Dinotta, Michele Malaguarnera   +7 more
doaj   +1 more source

Clinical usefulness of cancer markers in primary breast cancer [PDF]

, 2011
The aim of this study was to investigate the diagnostic power of CA 549, MSA and CA 15-3 in identifying breast cancer. The study included 232 patients of which 56 were healthy, 43 had benign breast cancer and 191 with other growths.
Clouth, Aline, Oremek, Gerhard Maximilian, Verring, A., Ziolkowski, Piotr   +3 more
core   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Restoring Conjunctival Tolerance by Topical Nuclear Factor–κB Inhibitors Reduces Preservative-Facilitated Allergic Conjunctivitis in Mice [PDF]

, 2014
Purpose.: To evaluate the role of nuclear factor–κB (NF-κB) activation in eye drop preservative toxicity and the effect of topical NF-κB inhibitors on preservative-facilitated allergic conjunctivitis.
Gabelloni, María Laura, Galletti, Jeremías Gastón, Giordano, Mirta Nilda, Guzman, Mauricio, Sabbione, Florencia, Trevani, Analía Silvina, Vanzulli, Silvia   +6 more
core   +1 more source

The power to predict with biomarkers: carbohydrate antigen 19-9 (CA 19-9) and carcinoembryonic antigen (CEA) serum markers in intrahepatic cholangiocarcinoma

Translational Gastroenterology and Hepatology, 2019
Carbohydrate antigen 19-9 (CA 19-9) and carcinoembryonic antigen (CEA) are the most studied tumor markers in intrahepatic cholangiocarcinoma (iCC) and are elevated in 85 and 40%, respectively (1). A recent publication proposed that serum biomarkers enhance the predictive power of the American Joint Committee on Cancer 8th edition (AJCC/UICC) and the ...
Jaklitsch M, Petrowsky H
openaire   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source