Results 1 to 10 of about 69 (67)
Cabergoline in Parkinson's disease [PDF]
Neurology, 1995 Contains fulltext : 21612___.PDF (Publisher’s version ) (Open Access)
Horstink, M.W.I.M. +2 more
+10 more sources
Understanding and treating ejaculatory dysfunction in men with diabetes mellitus
Andrology, Volume 11, Issue 2, Page 379-398, February 2023., 2023 Abstract Diabetes mellitus is a rapidly rising metabolic disorder with important systemic complications. Global figures have demonstrated the prevalence of diabetes mellitus has almost quadrupled from 108 million in 1980 to 422 million in 2014, with a current prevalence of over 525 million.
Ankit Desai +4 more
wiley +1 more source
A Practical Synthesis of Cabergoline [PDF]
The Journal of Organic Chemistry, 2002 Cabergoline is an N-acylurea derived from 9,10-dihydrolysergic acid, which is a potent prolactin inhibitor. It is marketed by Pharmacia as Dostinex for the treatment of hyperprolactinemia and is currently under active development for the treatment of a variety of CNS disorders.
Kevin E. Henegar +3 more
openaire +4 more sources
Cabergoline treatment in acromegaly: pros [PDF]
Endocrine, 2014 Cabergoline is an ergot-derived dopamine D2 receptor agonist which may be effective for the medical management of acromegaly. Its efficacy in reducing growth hormone and IGF-I levels, as well as its antiproliferative and pro-apoptotic effects on pituitary tumor cells, has been observed in several studies.
Ignacio Bernabeu +3 more
openaire +4 more sources
Cabergoline treatment in acromegaly: cons [PDF]
Endocrine, 2014 Many options are available for the treatment of acromegaly, including surgery, radiotherapy, and medical treatment. Cabergoline (CAB), a dopamine agonist with high affinity for dopamine receptor type 2, has been used both in monotherapy and in conjunction with somatostatin analogs (SSAs).
Leandro Kasuki +2 more
openaire +2 more sources
Cabergoline or bromocriptine for prolactinoma?
Medwave, 2016 Cabergoline and bromocriptine are among the most commonly used drugs to treat prolactinoma. Cabergoline is a long-acting dopamine receptor agonist which might offer advantages over bromocriptine. However, it is not clear if this translates into clinical benefits.
Victoria Castro-Gutiérrez +2 more
openaire +4 more sources
Cabergoline and gallbladder motility in healthy men [PDF]
European Journal of Endocrinology, 1999 Cozzi et al. (1) have shown that cabergoline, a synthetic ergoline derivative with an extremely long half-life (2, 3), is effective in the management of acromegalic patients resistant to somatostatin analogs, suggesting that cabergoline is a worthy therapeutic tool in these patients: it can be administered by the oral route and is much less expensive ...
R. Camisasca +4 more
openaire +3 more sources
Progress on the development of Class A GPCR‐biased ligands
British Journal of Pharmacology, EarlyView.Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales +20 more
wiley +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background Due to the high frequency of laminitis reported for both conditions, the relationship between pituitary pars intermedia dysfunction (PPID) and insulin dysregulation (ID), and the potential role of dopamine in modifying insulin secretion, requires further investigation.
Nicolas C. Galinelli +7 more
wiley +1 more source
Place of Cabergoline in Acromegaly: A Meta-Analysis [PDF]
The Journal of Clinical Endocrinology & Metabolism, 2011 Context: Cabergoline is widely considered to be poorly effective in acromegaly. Objective: The aim of this study was to obtain a more accurate picture of the efficacy of cabergoline in acromegaly, both alone and in combination with somatostatin ...
Philippe Chanson +2 more
openaire +3 more sources