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Cabergoline

Expert Opinion on Pharmacotherapy, 2000
Cabergoline (CAB) (1-[(6-allelylergolin-8 beta-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethyl-urea) is an ergoline derivative with potent, selective and long-lasting inhibitory activity on prolactin (PRL) secretion acting on dopamine receptors present in pituitary lactotrophes.
COLAO, ANNAMARIA   +2 more
openaire   +3 more sources

Cabergoline in acromegaly

Pituitary, 2016
Acromegaly, a rare disease due to growth hormone (GH) hypersecretion by a pituitary adenoma, is associated with severe comorbidity and premature death if not adequately treated. The usual first-line treatment is surgery. Various drugs, including somatostatin receptor ligands, dopamine agonists and GH receptor antagonists, are now available for use if ...
Emmanuelle Kuhn, Philippe Chanson
openaire   +3 more sources

Prolactinomas, cabergoline, and pregnancy

Endocrine, 2014
Hyperprolactinemia, frequently caused by a prolactinoma, is an important cause of infertility among young women. Dopamine agonists (DA) are the treatment of choice. Although cabergoline (CAB) is currently considered the gold standard DA, bromocriptine (BRC) remains the drug of choice for women desiring pregnancy, as it was proven to be safe in more ...
Andrea Glezer, Marcello D. Bronstein
openaire   +3 more sources

Cabergoline in prolactinomas

Neuro-Ophthalmology, 1999
Cabergoline is a potent, D2-selective new dopamine agonist with a half-life of 65 hours. We report two cases and review the literature on cabergoline in prolactinomas. Cabergoline appears to be more effective and better tolerated than bromocriptine, compliance may be improved, and costs are comparable.
Anna B. Fierz   +4 more
openaire   +2 more sources

Clinical Pharmacokinetics of Cabergoline

Clinical Pharmacokinetics, 2003
Cabergoline is a synthetic ergoline dopamine agonist with a high affinity for D(2) receptors indicated for use in both early and advanced Parkinson's disease and in hyperprolactinaemic disorders. Following oral administration, peak plasma concentrations of cabergoline are reached within 2-3 hours.
Del Dotto P, BONUCCELLI, UBALDO
openaire   +4 more sources

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