Results 61 to 70 of about 7,425 (188)

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 345-356, August 2026.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le, Sabrina Wong, Danica E. Johnson, Diana K. Orsini, Yang Jing Zheng, Kayla M. Teopiz, Christine E. Dri, Joshua D. Rosenblat, Roger S. McIntyre   +8 more
wiley   +1 more source

Effect of Cabergoline Treatment on Disease Control in Acromegaly Patients.

, 2022
The aim of this study was to evaluate the efficacy of cabergoline in normalizing plasma IGF-I levels in acromegaly patients with elevated IGF-I levels after surgery and/or SRL therapy. Acromegaly patients (n: 143) were evaluated retrospectively. Patients
Gul, Nurdan, Bilgic, Bilge, Uzum, Ayse Kubat, Hacisahinogullari, Hulya, Selcukbiricik, Özlem, Yalin, Gulsah Yenidunya, Aral, Ferihan, Tanakol, Refik   +7 more
core   +1 more source

The Effectiveness of Cabergoline for the Prevention of Ovarian Hyperstimulation Syndrome [PDF]

Iranian Journal of Medical Sciences, 2011
Type 2 receptors for vascular endothelial growth factor are believed to be involved in the pathophysiology of ovarian hyperstimulation syndrome (OHSS).
Marzieh Agha Hosseini, Ashraf Aleyasin, Atossa Mahdavi, Romina Nezami, Leila Safdarian   +4 more
doaj  

Is Hypercortisolism Treatable? Which Patients Should Be Treated and How—A Practical Guide for Clinicians

Diabetes, Obesity and Metabolism, Volume 28, Issue S4, Page 34-49, August 2026.
ABSTRACT Aim To provide a practical guide on when to suspect endogenous hypercortisolism, how to use the overnight 1‐mg dexamethasone suppression test (DST) for targeted case‐finding, and which patients are most likely to benefit from treatment.
Juan Pablo Frias
wiley   +1 more source

Cabergoline as a preventive migraine treatment: A randomized clinical pilot trial.

PLoS ONE
BackgroundBeneficial effects of dopamine agonist treatment on migraine have been reported but remain to be properly tested. The aim of this study was to examine the effect of cabergoline as preventive treatment for migraine.MethodsIn a double-blind ...
Astrid Johannesson Hjelholt, Flemming Winther Bach, Helge Kasch, Henrik Støvring, Troels Staehelin Jensen, Jens Otto Lunde Jørgensen   +5 more
doaj   +1 more source

Effect of dopamine agonist dose and treatment duration on fibrous tissue formation in prolactinomas

Alʹmanah Kliničeskoj Mediciny
Background: Currently, dopamine agonists are the established first-line therapy for prolactin-secreting pituitary adenomas. However, long-term treatment may be associated with the development of fibrotic changes within the adenoma tissue, which ...
Farida A. Nasybullina, Gulnar R. Vagapova, Bakhtiyar Yu. Pashayev, Regina R. Ashimova, Artur R. Khafizov   +4 more
doaj   +1 more source

Can acromegaly be controlled in all cases?

Journal of Neuroendocrinology, Volume 38, Issue 8, August 2026.
Abstract Acromegaly is a rare disease, due in most of the cases to a growth hormone (GH)‐secreting pituitary adenoma (PA), namely neuroendocrine tumour (PitNET). The treatment of patients with acromegaly is multimodal and multi‐step, including surgery, medical therapies, and radiotherapy.
Sabrina Chiloiro, Francesco Padovano Sorrentino, Alessandra Vicari, Antonella Giampietro, Pier Paolo Mattogno, Quintino Giorgio D'Alessandris, Rosalinda Calandrelli, Tommaso Tartaglione, Marco Gessi, Simona Gaudino, Laura De Marinis, Guido Rindi, Francesco Doglietto, Antonio Bianchi, Alfredo Pontecorvi   +14 more
wiley   +1 more source

Rolf Christian Gaillard (1944–2011): A builder of modern European endocrinology and neuroendocrinology

Journal of Neuroendocrinology, Volume 38, Issue 8, August 2026.
Abstract Rolf Christian Gaillard was a Swiss physician, scientist, and academic leader whose career contributed significantly to the development of modern European endocrinology and neuroendocrinology. Among his most remarkable qualities was an exceptional talent for organisation and institution‐building.
Philippe Chanson, Eduardo Spinedi, François Pralong   +2 more
wiley   +1 more source

Clinical profile and early therapeutic response to cabergoline of patients with hyperprolactinemia in a cameroonian population

The Pan African Medical Journal, 2020
Hyperprolactinemia is responsible for 20 to 25% of consultations of secondary amenorrhea and 17% for female infertility. Dopamine agonists are the gold standard treatment of hyperprolactinemia.
Martine Claude Etoa Etoga, Eugène Sobngwi, Pelagie Ngoune, Emmanuella Doh, Francine Mendane Mekobe, Noel Mbango-Ekouta, Mesmin Dehayem, Pascal Foumane, Jean Claude Mbanya   +8 more
doaj   +1 more source

Is Cabergoline Safe and Effective for Postpartum Lactation Inhibition? A Systematic Review

International Journal of Women's Health, 2020
Yang Yang,1 Isabelle Boucoiran,2 Karen J Tulloch,3 Vanessa Poliquin4 1University of Manitoba, Winnipeg, MB, Canada; 2Department of Obstetrics & Gynecology, Université de Montréal, Montreal, QC, Canada; 3BC Women’s Hospital ...
Yang Y, Boucoiran I, Tulloch KJ, Poliquin V   +3 more
doaj