Results 21 to 30 of about 76,362 (268)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Fire-resistance design and experimental research for the stay cables of super-long span cable-stayed bridge

open access: yesAdvances in Bridge Engineering
The cables are crucial to the service life of cable supported bridges. Fire accidents involving bridge cables may cause severe damage, impacting the structural integrity and performance of bridges, and therefore requires thorough attention and research ...
Kongjian Shen   +6 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Numerical Study of Bending Behavior for 66 kV Submarine Cables

open access: yes한국해양공학회지
Submarine cables operate in complex marine environments and are repeatedly subjected to lateral loads from ocean currents, waves, and seabed irregularities.
YunJae Kim   +4 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

Thermal Characteristic of Fire Resistance Electrical Cable for Residential Wiring Installation [PDF]

open access: yesJEMMME (Journal of Energy, Mechanical, Material, and Manufacturing Engineering), 2018
The objective of the research was to investigate thermal characteristic of electrical cable for residential wiring installation in order to acquire the initial data for fire protection study especially connected to short circuit.
Yunita Sari, Mochammad Syamsum Ma'arif
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Analysis of Weak Section of Submarine Cable Inside J-Tube of Offshore Wind Farm

open access: yesIEEE Access
Global warming and environmental issues have necessitated ecofriendly energy generation from offshore wind farms. In this context, submarine cables for offshore wind farms and weak sections of the submarine cables inside the J-tube, which transmit power ...
Seung-Won Lee   +5 more
doaj   +1 more source

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