Results 21 to 30 of about 4,594 (169)

Transfusion-Transmitted Cache Valley Virus Infection in a Kidney Transplant Recipient With Meningoencephalitis. [PDF]

Clin Infect Dis, 2023
Abstract Background Cache Valley virus (CVV) is a mosquito-borne virus that is a rare cause of disease in humans. In the fall of 2020, a patient developed encephalitis 6 weeks following kidney transplantation and receipt of multiple blood transfusions.
Al-Heeti O, Wu EL, Ison MG, Saluja RK, Ramsey G, Matkovic E, Ha K, Hall S, Banach B, Wilson MR, Miller S, Chiu CY, McCabe M, Bari C, Zimler RA, Babiker H, Freeman D, Popovitch J, Annambhotla P, Lehman JA, Fitzpatrick K, Velez JO, Davis EH, Hughes HR, Panella A, Brault A, Staples JE, Gould CV, Tanna S.   +28 more
europepmc   +5 more sources

Cache Valley virus: A scoping review of the global evidence. [PDF]

Zoonoses Public Health, 2019
AbstractCache Valley virus (CVV) is a mosquito‐borne RNA virus detected throughout North America, Central America and parts of South America. A limited number of human case reports have described severe illness. CVV infection has been associated with outbreaks of congenital defects in small ruminants in Canada and the United States.
Waddell L, Pachal N, Mascarenhas M, Greig J, Harding S, Young I, Wilhelm B.   +6 more
europepmc   +4 more sources

Ovine fetal immune response to Cache Valley virus infection. [PDF]

J Virol, 2013
ABSTRACTCache Valley virus (CVV)-induced malformations have been previously reproduced in ovine fetuses. To evaluate the development of the antiviral response by the early, infected fetus, before the development of immunocompetency, ovine fetuses at 35 days of gestation were inoculatedin uterowith CVV and euthanized at 7, 10, 14, 21, and 28 days ...
Rodrigues Hoffmann A, Dorniak P, Filant J, Dunlap KA, Bazer FW, de la Concha-Bermejillo A, Welsh CJ, Varner P, Edwards JF.   +8 more
europepmc   +4 more sources

Fatal Cache Valley virus meningoencephalitis associated with rituximab maintenance therapy. [PDF]

Am J Hematol, 2018
Yang Y, Qiu J, Snyder-Keller A, Wu Y, Sun S, Sui H, Dean AB, Kramer L, Hernandez-Ilizaliturri F.   +8 more
europepmc   +4 more sources

Replication Kinetics of a Candidate Live-Attenuated Vaccine for Cache Valley Virus in <i>Aedes albopictus</i>. [PDF]

Vector Borne Zoonotic Dis, 2022
Background: The emergence or re-emergence of several orthobunyaviruses (order: Bunyavirales; family: Peribunyaviridae), including Cache Valley virus (CVV) and Oropouche virus, warrants the development and evaluation of candidate live-attenuated vaccines (LAVs).
Ayers VB, Huang YS, Dunlop JI, Kohl A, Brennan B, Higgs S, Vanlandingham DL.   +6 more
europepmc   +3 more sources

A novel cause of chronic viral meningoencephalitis: Cache Valley virus. [PDF]

Ann Neurol, 2017
ObjectiveImmunodeficient patients are particularly vulnerable to neuroinvasive infections that can be challenging to diagnose. Metagenomic next generation sequencing can identify unusual or novel microbes and is therefore well suited for investigating the etiology of chronic meningoencephalitis in immunodeficient patients.MethodsWe present the case of ...
Wilson MR, Suan D, Duggins A, Schubert RD, Khan LM, Sample HA, Zorn KC, Rodrigues Hoffman A, Blick A, Shingde M, DeRisi JL.   +10 more
europepmc   +6 more sources

Aedes mosquito saliva modulates Rift Valley fever virus pathogenicity. [PDF]

PLoS Neglected Tropical Diseases, 2013
BACKGROUND: Rift Valley fever (RVF) is a severe mosquito-borne disease affecting humans and domestic ruminants. Mosquito saliva contains compounds that counteract the hemostatic, inflammatory, and immune responses of the host.
Alain Le Coupanec, Divya Babin, Laurence Fiette, Grégory Jouvion, Patrick Ave, Dorothee Misse, Michèle Bouloy, Valerie Choumet   +7 more
doaj   +1 more source

Screening and Identification of Multiple Peptides Homologous to the Fusion Glycoprotein Gc of Schmallenberg Virus Able to Inhibit Viral Infection. [PDF]

Transbound Emerg Dis
Arthropod‐borne viruses have been responsible for several emerging infections, causing a global issue in both human and veterinary fields. Within the Orthobunyaviruses, a novel and major member is the Schmallenberg virus (SBV) first detected in central Europe in 2011, and soon after was able to spread all over the continent by causing severe infection ...
Zannella C, Grazioso R, Chianese A, Iovane V, Santella B, Montagnaro S, Greco G, Pagnini U, Franci G, Filippis A, Iovane G, Isernia C, Galdiero M.   +12 more
europepmc   +2 more sources

Clinical Translation of Extracellular Vesicles

Advanced Healthcare Materials, Volume 12, Issue 28, November 10, 2023., 2023
In this perspective, the current trends, emerging trends and challenges associated with the clinical translation of extracellular vesicles (EVs) are discussed, and completed and selected ongoing clinical trials using EVs are highlighted. Abstract Extracellular vesicles (EVs) occur in a variety of bodily fluids and have gained recent attraction as ...
Aayushi Ghodasara, Aun Raza, Joy Wolfram, Carlos Salomon, Amirali Popat   +4 more
wiley   +1 more source

Impact of weight gain with dolutegravir on antiretroviral adherence and viral suppression in four African countries

HIV Medicine, Volume 24, Issue 10, Page 1066-1074, October 2023., 2023
Abstract Objective We hypothesized that total body weight (TBW) gain after switching antiretroviral therapy (ART) regimen to tenofovir disoproxil fumarate/lamivudine/dolutegravir (TLD) may negatively impact ART adherence and viral load (VL) and therefore sought to examine these associations.
Matthew L. Romo, Allahna L. Esber, John Owuoth, Jonah Maswai, Valentine Sing'oei, Michael Iroezindu, Emmanuel Bahemana, Hannah Kibuuka, J. Sean Cavanaugh, Neha Shah, Julie A. Ake, Trevor A. Crowell, on behalf of the AFRICOS Study Group   +12 more
wiley   +1 more source