The Role of Orthobunyavirus Glycoprotein Gc in the Viral Life Cycle: From Viral Entry to Egress [PDF]
MoleculesOrthobunyavirus refers to the virus members within the Genus Orthobunyavirus, which is the largest virus genus in the Family Peribunyaviridae and even Class Bunyaviricetes.
Han Gao +2 more
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Genomic characterization of arboviruses discovered between the 1950s and 1980s [PDF]
Journal of VirologyArthropod-borne viruses (arboviruses) pose a major threat to global public health, impacting both human and animal health. Genomic characterization is important for arboviruses because it allows for an understanding of their evolution and improves timely
Ingra M. Claro +7 more
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Reverse Genetics System for Shuni Virus, an Emerging Orthobunyavirus with Zoonotic Potential
Viruses, 2020 The genus Orthobunyavirus (family Peribunyaviridae, order Bunyavirales) comprises over 170 named mosquito- and midge-borne viruses, several of which cause severe disease in animals or humans. Their three-segmented genomes enable reassortment with related
Judith Oymans +2 more
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Molecular identification and cross-species transmission effects analysis of a novel Orthobunyavirus isolated from Geese in China [PDF]
Poultry ScienceOrthobunyavirus is a class of RNA viruses that includes hundreds of viruses, many of which are important zoonotic pathogens causing clinical symptoms in livestock and humans.
Huiping Liang +12 more
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Probing orthobunyavirus reassortment using Bunyamwera and Batai viruses as models. [PDF]
PLoS Neglected Tropical DiseasesReassortment is a critical evolutionary mechanism for segmented viruses, enabling the exchange of intact genome segments during co-infection and driving orthobunyavirus evolution; however, the molecular mechanisms underpinning this process remain unclear.
James M Bowen +7 more
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The La Crosse virus Gc head domain is a major determinant of infection and pathogenesis [PDF]
Journal of VirologyHow orthobunyaviruses establish infections and disseminate to cause disease is not well understood. In a previous study using the in vivo evolution of La Crosse virus (LACV), we discovered a cluster of mutations localizing to the LACV Gc head domain ...
Ariana Dedvukaj +6 more
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Novel Orthobunyavirus in Cattle, Europe, 2011
Emerging Infectious Diseases, 2012 In 2011, an unidentified disease in cattle was reported in Germany and the Netherlands. Clinical signs included fever, decreased milk production, and diarrhea.
Bernd Hoffmann +2 more
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INVESTIGAÇÃO SOROLÓGICA PARA AS ARBOVIROSES EM ÁREAS DE EXPLORAÇÃO MINERAL NO ESTADO DO PARÁ
Brazilian Journal of Infectious Diseases, 2023 Introdução: O estado do Pará vem sofrendo grandes transformações ambientais, dentre elas a exploração mineral e o desmatamento, o que aumenta o risco de infecção humana por arbovírus. Assim, objetiva-se demonstrar, através da presença de anticorpos IgM e
Letícia Françadas Mercês +7 more
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Viruses, 2021 Reassortment is a viral genome-segment recomposition known for many viruses, including the orthobunyaviruses. The co-infection of a host cell with two viruses of the same serogroup, such as the Bunyamwera orthobunyavirus and the Batai orthobunyavirus ...
Anna Heitmann +9 more
doaj +1 more source
No Evidence of Ntwetwe Virus Infections in Children Presenting to Kiboga Hospital, Uganda
Tropical Medicine and Infectious Disease, 2022 We investigated whether Ntwetwe virus—a novel orthobunyavirus discovered in a Ugandan girl with a fatal encephalopathy—was a common reason for hospital admission for children to Kiboga hospital, Uganda. A case–control was conducted between September 2019
Arthur W. D. Edridge +10 more
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