Results 201 to 210 of about 539,727 (292)

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

Combined computational, rational, and empirical design of boiling-resistant keratinase. [PDF]

Appl Environ Microbiol
Yang Y, Luo Y, Ding Y, Yao Y, Liu J, Xu Z, Li Y, Li H, Gan F, Tang X-F, Tang B.   +10 more
europepmc   +1 more source

Electrical Control of the Transduction Channels’ Gating Force in Mechanosensory Hair Cells

Advanced Science, EarlyView.
The inner ear's hair cells rely on mechanosensitive ion channels to convert vibrations of their hair‐bundle into electrical signals. We show that varying the electrical potential (U) across the sensory epithelium modulates a key determinant of mechanosensitivity—the gating force (FG)—by modulating the gating swing (d), ranging from the size of the ...
Achille Joliot, Laure Stickel, Pascal Martin   +2 more
wiley   +1 more source

Improvement mechanism of cellulose nanocrystal in coordination with calcium ions on the thermal gelation of soybean protein amyloid fibrils. [PDF]

Food Chem X
Zhu S, Song X, Zhong K, Lin L, Huang Y, Zha W, Liu Y, Lan W, Xiao Y.   +8 more
europepmc   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Evaluating peripartum calcium administration strategies to improve sow farrowing performance and piglet livability. [PDF]

Transl Anim Sci
Jenkins AK, Collier SM, Virdis S, Cataldo OJ, Tokach MD, DeRouchey JM, Woodworth JC, Gaffield KN, Gebhardt JT, Goodband RD, Coble KF, Corns PJ, Karl J, Bradley T, Soto JA, Bents A.   +15 more
europepmc   +1 more source

Solubility of CaS in Molten CaCl2

Solubility of CaS in Molten CaCl2
In order to check the solubility of CaS during sulfide reduction in molten CaCl2, the mixture of CaCl2 and a small amount of CaS was melted in Ar at the range from 1123 K to 1223 K. The melt was sampled by quartz tube and rapidly solidified. The solidified samples showed a lamella structure with CaS particles, which results in a simple eutectic ...
openaire  

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

Three-Dimensional Bioprinting of Regenerative Cartilage Constructs with Directional Ionically Derived Stiffness Gradients. [PDF]

J Funct Biomater
Hosseini M, Dimaraki A, van Osch GJVM, Fratila-Apachitei LE, Díaz-Payno PJ, Zadpoor AA.   +5 more
europepmc   +1 more source

A Microfluidic Digital Shutter of Liquid–Liquid Interface for Fabrication of Multifaceted Hydrogel Microfiber Structure

Advanced Science, EarlyView.
A programmable passive digital shutter based on multiphase liquid–liquid interface dynamics is introduced for precise fabrication of hydrogel microfibers. By modulating the shutter operation, microfibers with tunable geometry—including linear, helical, tadpole‐like, and spherical forms—are produced.
Dongrui Zhang, Jiangyue Liu, Hao Ye, Yu Shen, Haoran Su, Zhuqing Liang, Kexin Li, Xing Zhang, Shiyi Yang, Yunfei Lu, Zhexi Zhang, Sihang Liu, Yi Huang, Xiao Liu, Yubo Fan   +14 more
wiley   +1 more source