Results 201 to 210 of about 539,116 (310)

DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics

open access: yesAdvanced Science, EarlyView.
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei   +12 more
wiley   +1 more source

Calcium Reduction of TiS2 in CaCl2 Melt

open access: yesCalcium Reduction of TiS2 in CaCl2 Melt
In this study, we reduce TiS2 to Ti via both calciothermic reduction and electrolysis in a CaCl2 melt. Upon calcium reduction at 1133 K in CaCl2 melt, the concentration of sulfur decreases to 0.03 mass% S when an amount greater than twice the stoichiometric calcium amount is added.
openaire  

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

open access: yesAdvanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi   +7 more
wiley   +1 more source

Local cation-clamping distorts and softens RNA duplex. [PDF]

open access: yesCommun Biol
Zhang C   +6 more
europepmc   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

open access: yesAdvanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee   +11 more
wiley   +1 more source

Bioprinting of Nanocellulose Hydrogels for Photobiocatalysis Under Continuous Flow. [PDF]

open access: yesACS Sustain Chem Eng
Malihan-Yap L   +9 more
europepmc   +1 more source

Studying Macromolecular Composition in Cell–Cell Interfaces Using 3D Membrane Reconstitution Systems

open access: yesAdvanced Science, EarlyView.
A comprehensive understanding of the interactions between proteins, lipids and glycocalyx components at the immune synapse is still lacking. Here, an artificial and a semi‐artificial model contact system were established to reconstitute the cell‐cell contact in 3D. The model systems enable the examination of macromolecule enrichment or depletion at the
Franziska Ragaller   +9 more
wiley   +1 more source

Local modifications in tissular conditions before PFA increases acute lesion size. [PDF]

open access: yesHeart Rhythm O2
Amorós-Figueras G   +6 more
europepmc   +1 more source

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