Results 91 to 100 of about 413,656 (244)

Trustworthy Multimodal Attention Framework for Creep Rupture Life Prediction Under Data‐Scarce Conditions: A Case Study on IN718

Advanced Science, EarlyView.
An attention‐based multimodal deep learning framework is developed to predict the creep life of Ni‐based superalloys by fusing processing parameters with microstructural micrographs. The model achieves high accuracy (R2 = 0.92), aligns with metallurgical principles by capturing δ‐phase influence, and incorporates uncertainty quantification, offering a ...
Haopeng Lv, Dayong Wu, Ziyuan Rao, Qian Wang, Haikun Ma, Jie Kang, Wang Li, Huicong Dong, Yandong Wang, Zhinan Yang, Ru Su   +10 more
wiley   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

Hyper-Data: A Matlab based optimization software for data-driven hyperelasticity

SoftwareX
In this work, a parameter identification software for the data-driven hyperelasticity frameworks proposed by Dal et al. (Journal of the Mechanics and Physics of Solids 179, 105381, 2023), and Tikenoğullarıet al.
Recep Durna, Alp Kağan Açan, Oğuz Ziya Tikenoğulları, Hüsnü Dal   +3 more
doaj   +1 more source

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

Low Latency Global Carbon Budget Reveals Late 2024 Carbon Losses and Contrasting Early 2025 Land Sink Recovery Signals

Advanced Science, EarlyView.
Low latency carbon budget estimates for July 2024–June 2025 combine atmospheric CO2 growth rates, fossil emissions, ocean uptake, DGVM land fluxes, and OCO‐2 inversions. The budget shows that late‐2024 land carbon losses dominate the annual anomaly, while early‐2025 recovery differs between bottom‐up models and top‐down inversions, especially in ...
Piyu Ke, Philippe Ciais, Yitong Yao, Stephen Sitch, Wei Li, Xiaomeng Du, Xiaofan Gui, Ben Poulter, Thomas Colligan, Auke M. van der Woude, Joram Hooghiem, Wouter Peters, Zhu Liu, Zhu Deng, Zhe Jin, Xiangjun Tian, Yilong Wang, Junjie Liu, Sudhanshu Pandey, Chris O'Dell, Jiang Bian, John Miller, Xin Lan, Jefferson Goncalves De Souza, Michael O'Sullivan, Pierre Friedlingstein, Julien Alléon, Yi Xi, Daniel S. Goll, Lei Zhu, Guido R. van der Werf, Shilong Piao, Frédéric Chevallier   +32 more
wiley   +1 more source

Intra-oral scanning and CAD/CAM prosthesis fabrication

Annali di Stomatologia, 2018
The acronym Cad-Cam stands for Computer-Aided Design and Computer-Aided Manufacturing. In 1970, Dr. Francois Duret and his colleagues were the first to develop a Cad-Cam dental system, later named the Sopha system (Sopha BioConcept, Inc. Los Angeles). In
Enrico Moglioni, Luca dal Carlo, Mike Shulman, Marco Pasqualini, Franco Rossi, Carlo Cosma, Flavio Lico, Paolo Diotallevi   +7 more
doaj   +1 more source

Dental Restoratives Manufactured by CAD/CAM System : 1. Adaptation of Titanium Copings and Observation of Bonding Interface between Ceramics and Stain Porcelain [PDF]

, 2006
P(論文)In this study, a sample of titanium crown made by using DECSY, a dental CAD/CAM system, and one made by casting were compared to examine the adaptation, and the bonding interface of a special ceramic block and stain porcelain after baking was ...
岡田, 英俊, 9685, 9686, 9683, 9684, 9689, 9700, 9701, 9687, 9688, 9681, 9682, イシダ, ヨシノリ, 9680, フクイ, カズノリ, オカダ, ヒデトシ, OKADA, Hidetoshi, 覚本, 嘉美, 9696, 9697, 9694, KAKUMOTO, Yoshimi, 9695, FUKUI, Kazunori, NAGAYAMA, Katsuya, ノグチ, ヒロシ, 9679, 福井, 和徳, 9698, リュウカタ, イチロウ, 9699, 石田, 喜紀, カクモト, ヨシミ, 長山, 克也, 9692, 9693, 龍方, 一朗, 9690, ナガヤマ, カツヤ, 9691, カゲヤマ, マサヤス, 野口, 博志, NOGUCHI, Hiroshi, 影山, 勝保, RYUKATA, Ichiro, KAGEYAMA, Masayasu, ISHIDA, Yoshinori, 9702   +47 more
core  

Triple‐Level Content‐Addressable Vertical NAND Flash Memory

Advanced Science, EarlyView.
Commercial triple‐level‐cell V‐NAND flash memory is transformed into a compact content‐addressable memory by directly exploiting its eight threshold‐voltage states. A parity‐split search scheme preserves storage density while enabling reliable multi‐level and don't‐care matching. Parallel word‐line search delivers up to 24‐fold higher throughput and 54.
Sung‐Ho Park, Jiseong Im, Yeongheon Yang, Ryun‐Han Koo, Jonghyun Ko, Mingyun Oh, Dongbeen Shin, Gyuweon Jung, Jong‐Ho Lee   +8 more
wiley   +1 more source

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

Collagen‐Binding IL‐15 Immunocytokine Armed Oncolytic Adenovirus Establishes a Self‐Reinforcing Immunostimulatory Milieu to Potentiate Antitumor Immunity

Advanced Science, EarlyView.
Repurposing the dense tumor stroma from a physical barrier into an anchoring scaffold, an engineered oncolytic adenovirus encoding IL15C‐CBD overcomes the immunosuppressive microenvironment in triple‐negative breast cancer. Intratumoral viral replication secretes this collagen‐anchored immunocytokine, forming a localized cytokine depot.
Yaqi Yang, Xiaoxiao Liu, Junqiang Ding, Jinliang Xu, Jianhua Zhang, Hanchang Zhang, Rong Yang, Sha Li, Lu Zheng, Runping Su, Yue Zhao, Jianxiao Wu, Hao Li, Changyou Zhan, Xihui Gao   +14 more
wiley   +1 more source