Results 41 to 50 of about 979,106 (300)

Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need [PDF]

open access: yes, 2018
The diagnostic management of patients with angina pectoris typically centres on the detection of obstructive epicardial CAD, which aligns with evidence-based treatment options that include medical therapy and myocardial revascularisation.
Berry, Colin   +2 more
core   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

A Predictive Design Framework for Tunable Structural Colour Inspired by Morpho Nanostructures

open access: yesAdvances in Materials Science and Engineering
Structural colour arises from light interacting with nanoscale architectures, yet generalizable design rules for engineering such effects remain limited.
Tobias Rosnitschek   +4 more
doaj   +1 more source

Ultra-high resolution facial texture reconstruction from a single image

open access: yesComputational Visual Media
Advances in mobile cameras have made it easier to capture ultra-high resolution (UHR) portraits. However, existing face reconstruction methods lack specific adaptations for UHR input (e.g., 4096 × 4096), leading to under-use of high-frequency details ...
Hongxiang Huang   +6 more
doaj   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Epidemiology of canine atopic dermatitis [PDF]

open access: yes, 2007
Canine atopic dermatitis (CAD) is a chronic, allergic skin disease associated with IgE-mediated reactions to environmental allergens. Atopic dermatitis/eczema in humans shares many similarities with CAD and is an increasing problem in industrialized ...
Nødtvedt, Ane
core  

Genetic variants of the promoter of the heme oxygenase-1 gene and their influence on cardiovascular disease (The Ludwigshafen risk and cardiovascular health study) [PDF]

open access: yes, 2009
Background Heme oxygenase-1 is an inducible cytoprotective enzyme which handles oxidative stress by generating anti-oxidant bilirubin and vasodilating carbon monoxide.
Lüblinghoff, Nicola   +7 more
core   +2 more sources

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

Federated Learning-Oriented Edge Computing Framework for the IIoT

open access: yesSensors
With the maturity of artificial intelligence (AI) technology, applications of AI in edge computing will greatly promote the development of industrial technology. However, the existing studies on the edge computing framework for the Industrial Internet of
Xianhui Liu   +3 more
doaj   +1 more source

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