Results 51 to 60 of about 208,469 (265)

Training for Evolving. The Architectural Project from CAD to CAM

open access: yesIn_Bo, 2020
Digital tools have considerably expanded the possibilities of managing transformation and architectural construction projects, offering the opportunity to obtain virtual models that can also approximate projects behaviour before the construction step ...
Nicola Parisi
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Application of the rapid prototyping technique to design a customized temporomandibular joint used to treat temporomandibular ankylosis

open access: yesIndian Journal of Plastic Surgery, 2009
Anthropometric variations in humans make it difficult to replace a temporomandibular joint (TMJ), successfully using a standard “one-size-fits-all” prosthesis.
Suresh M. Chaware   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

An Intelligent Support Method for the Formation of Control Actions in Proactive Management of Complex Systems

open access: yesApplied System Innovation
This paper addresses the problem of ensuring the continuous operation of cyber–physical systems (CPS) under conditions of component degradation and wear.
Vladimir Artyushin   +4 more
doaj   +1 more source

Risk Factors for Acute Kidney Injury After Hip Fracture Surgery in the Elderly Individuals

open access: yesGeriatric Orthopaedic Surgery & Rehabilitation, 2012
Objective: We aimed to evaluate possible risk factors assocıated wıth acute kidney injury (AKI) after hip fracture surgery in the elderly individuals. Design: Level II diagnostic study, evidence obtained from prospective cohort study from 1 center with ...
Cagatay Ulucay   +6 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

A Flexible Solid 3D Model Reconstruction System for Mechanical CAD /CAM Systems [PDF]

open access: yes한국정밀공학회지, 2019
Three-dimensional CAD models are usually used by designers because of their applications in the areas of CAD/CAM/ CAE/CAQ. A desirous trend to create this model, long been studied by scientists globally, is 3D model reconstruction from views.
Long Hoang, Long Banh Tien
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

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