Results 81 to 90 of about 9,876 (239)
Abstract INTRODUCTION Global life expectancy has steadily increased in recent decades, resulting in a significant rise in the number of individuals aged 80 years and older. This trend is also evident in Latin America, where life expectancy is improving, though at varying rates across countries and regions.
Yakeel T. Quiroz+18 more
wiley +1 more source
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy [PDF]
Introduction. Fast and precise diagnostics of the disease from the large group of adult leukoencephalopathy is difficult but responsible job, because the outcome of the disease is very often determined by its name.
Krsmanović Željko+7 more
doaj +1 more source
Abstract INTRODUCTION Alzheimer's disease neuropathologic change (ADNC), Lewy body disease (LBD), and vascular neuropathologies occur together. Previous studies have been limited by a large majority of participants with severe dementia or advanced stages of pathologies, which limits the detectability of cognitive effects from vascular neuropathologies.
Cellas A. Hayes+9 more
wiley +1 more source
Peripheral neuropathy in a case with CADASIL: a case report
Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is characterized clinically by central nervous system dysfunctions. It is unclear whether CADASIL is involved in peripheral neuropathy.
Yusuke Sakiyama+10 more
doaj +1 more source
Virchow-Robin spaces : an anatomic variant or a pathologic sign? [PDF]
Virchow-Robin spaces surround blood vessels. Their walls are formed by prolongations of the pia mater and they have no communication with the subarachnoid space. VRS are often seen as well-delineated foci of cerebrospinal fluid signal on MR images.
core
Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) mainly manifests with cognitive impairment.
Jingjing Su+10 more
doaj +1 more source
The effect of NOTCH3 pathogenic variant position on CADASIL disease severity: NOTCH3 EGFr 1–6 pathogenic variant are associated with a more severe phenotype and lower survival compared with EGFr 7–34 pathogenic variant [PDF]
Purpose: CADASIL is a small-vessel disease caused by a cysteine-altering pathogenic variant in one of the 34 epidermal growth factor-like repeat (EGFr) domains of the NOTCH3 protein.
A. Federico+10 more
core +1 more source
Stroke and associated comorbidities in Southeast Asian countries
Different diseases can act as comorbid factors of stroke. Among them, hyperglycemia, hypertension, hyperlipidemia, atrial fibrillation, cancer, and chronic kidney disease act as major comorbidities. Whereas migraine, Fabry disease, Moyamoya disease, sickle cell disease, cerebral autosomal dominant arteriopathy with subcortical infarcts and ...
Aishika Datta+9 more
wiley +1 more source
Novel mutations in HTRA1‐related cerebral small vessel disease and comparison with CADASIL
Objective There is evidence showing both heterozygous HTRA1 and homozygous HTRA1 mutations as causal for familial cerebral small vessel disease (CSVD).
Chen Zhang+8 more
doaj +1 more source
Free Water as a Marker of Early Small Vessel Disease in Healthy Aging
ABSTRACT Background Brain aging is associated with cerebrovascular changes and related microstructural pathology. In this context, research indicates that small vessel disease (SVD) is characterized by increases in extracellular free water (FW). Methods We examined 94 individuals with early signs of small vessel disease (eSVD; Mage = 69.47 years, SDage
Manuel Leitner+6 more
wiley +1 more source