Results 61 to 70 of about 6,349 (169)

Peripheral neuropathy in a case with CADASIL: a case report

BMC Neurology, 2018
Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is characterized clinically by central nervous system dysfunctions. It is unclear whether CADASIL is involved in peripheral neuropathy.
Yusuke Sakiyama, Eiji Matsuura, Yoshimitsu Maki, Akiko Yoshimura, Masahiro Ando, Miwa Nomura, Kazuya Shinohara, Ryuji Saigo, Tomonori Nakamura, Akihiro Hashiguchi, Hiroshi Takashima   +10 more
doaj   +1 more source

Psychotherapy and inhibitory control: Insights from fMRI research

Psychiatry and Clinical Neurosciences, Volume 80, Issue 6, Page 502-509, June 2026.
Aim Despite the widespread clinical use of psychotherapy, the neural mechanisms linking treatment to changes in inhibitory control networks supporting self‐regulation remain unclear. This study addresses this gap by meta‐analyzing neuroimaging research on how psychotherapy affects brain regions involved in inhibitory control.
Gioele Gavazzi, Ozge Ozkan, Viola Benedetti, Fabio Giovannelli, Valdo Ricca, Maria Pia Viggiano   +5 more
wiley   +1 more source

A Report of Accelerated Coronary Artery Disease Associated with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy

Case Reports in Cardiology, 2015
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common heritable form of vascular dementia and it is caused by mutations in the NOTCH3 gene.
Courtney B. Rubin, Virginia Hahn, Taisei Kobayashi, Andrew Litwack   +3 more
doaj   +1 more source

Homozygous NOTCH3 p.R587C mutation in Chinese patients with CADASIL: a case report

BMC Neurology, 2020
Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited small vessel disease caused by mutations in NOTCH3 gene with remarkable phenotypic heterogeneity.
Ruojie He, Huan Li, Yiming Sun, Menglong Chen, Liang Wang, Yuling Zhu, Cheng Zhang   +6 more
doaj   +1 more source

Dimerization‐dependent NOTCH receptor transactivation unveils a class of highly selective NOTCH signalling inhibitors

The FEBS Journal, Volume 293, Issue 10, Page 2825-2844, May 2026.
NOTCH signalling is indispensable for tissue homeostasis and, consequently, corruption of its normal function promotes numerous diseases, including cancer. However, the development of targeted therapies has been hampered by inefficacy and overt toxicity. Here, we show that NOTCH receptor dimerization is necessary for receptor transactivation, which has
Xinxin Liu, Haijiang Wang, Gunja Mishra, Lin‐Ting Wu, Chao Li, Maarten van Dinther, Jin Liu, Manuel A.F.V. Gonçalves, Peter ten Dijke, David A. Baker   +9 more
wiley   +1 more source

Pregnancy in CADASIL

, 2017
Objectives: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited cerebral small vessel disease caused by NOTCH3 gene mutations.
FEDERICO, ANTONIO, Rinnoci, V., I. Donnini, Pantoni, L., L. Pantoni, Nannucci, S., DOTTI, MARIA, Mariani, G., R. Valenti, VALENTI, ROBERTO, M. T. Dotti, Inzitari, D., Donnini, I., F. Pescini, S. Nannucci, A. Federico, G. Mariani, Pescini, F., S. Bianchi, BIANCHI, SILVIA, V. Rinnoci, D. Inzitari   +21 more
core   +1 more source

CADASIL AND BIPOLAR AFFECTIVE DISORDER [PDF]

, 2019
Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is a rare monogenic disorder caused by mutations in the NOTCH3 gene.
A. Millar, Zachary, Zaman, Rashid, Lim, Hong Kai   +2 more
core   +1 more source

Targeted next generation sequencing identifies novel NOTCH3 gene mutations in CADASIL diagnostics patients [PDF]

, 2016
BACKGROUND\ud \ud Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a monogenic, hereditary, small vessel disease of the brain causing stroke and vascular dementia in adults.
Robert A. Smith, Lyn R. Griffiths, Griffiths, Lyn R., Neven Maksemous, Maksemous, Neven, Larisa M. Haupt, Smith, Robert A., Haupt, Larisa M.   +7 more
core   +1 more source

Assessing changes on large cerebral arteries in CADASIL: Preliminary insights from a case-control analysis

Journal of Stroke and Cerebrovascular Diseases
Introduction: Parent large brain arteries are intimately related to their offspring's small arteries. Whether the CADASIL phenotype is confined to small vessels is unclear, and the involvement of large arteries in CADASIL has not been systematically ...
Edgar R. Lopez-Navarro, MD, Silvia V. Mayer, MD, Brenno R. Barreto, MD, Kevin H. Strobino, MPH, Antonio Spagnolo-Allende, MD, Pedro G. Bueno, MD, Kursat Gurel, MD, Khrystyna Kozii, MD, Salwa Rahman, MD, Farid Khasiyev, MD, Jane S. Paulsen, PhD, Jose Gutierrez, MD, MPH   +11 more
doaj   +1 more source

On the diagnosis of CADASIL.

, 2009
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a genetic arteriopathy related to Notch3 mutations, is difficult to diagnosis.
Elena Erro, Manuel Seijo, Galloway, EG, Cervelló, A, López-Valdés, E, Israel Ampuero, Eva García Galloway, Ángeles Cervelló, de Yébenes, JG, Eva López-Valdés, Rivas, GG, José Luis Lopez Sendón, Morlán, L, Seijo, M, Alegre-Abarrategui, J, Ros, R, Lorenzo Morlán, España, A, Erro, E, Jarauta, F, Justo García de Yébenes, David G. Muñoz, Yolanda Aladro, Zabala, A, Ampuero, I, Raquel Ros, Antxon Zabala, Guillermo García Rivas, Rodal, I, Aladro, Y, Fernando Jarauta, Caminero, AB, Sendón, JL, Antonio España, Javier Alegre-Abarrategui, Muñoz, DG, Ana Belén Caminero, Izaskun Rodal   +37 more
core   +1 more source