Results 81 to 90 of about 8,915 (192)

Clinical and genetic characterization of leukoencephalopathies in adults [PDF]

open access: yes, 2017
Leukodystrophies and genetic leukoencephalopathies are a rare group of disorders leading to progressive degeneration of cerebral white matter. They are associated with a spectrum of clinical phenotypes dominated by dementia, psychiatric changes, movement
Adams, M   +28 more
core   +1 more source

Diagnosis in vascular dementia, applying ‘Cochrane diagnosis rules’ to ‘dementia diagnostic tools’ [PDF]

open access: yes, 2017
In this issue of Clinical Science, Biesbroek and colleagues describe recent work on magnetic resonance imaging (MRI)-based cerebral lesion location and its association with cognitive decline.
McCleery, Jenny, Quinn, Terence J.
core   +1 more source

CADASIL

open access: yes, 2012
Introduction: Cerebral autosomal dominant arteriopathy with subcortical infarctions and leukoencephalopathy CADASIL is a single gene disorder of the cerebral small blood vessels caused by mutations in NOTCH3 gene. The disease has been recently described and the exact prevalence is unknown currently, but the number of the reported cases is increasing as
  +5 more sources

Atypical clinical cases of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)

open access: yesАнналы клинической и экспериментальной неврологии, 2017
C Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary CNS disease with autosomal dominant inheritance caused by NOTCH3 gene mutations. In classic cases, CADASIL manifests with headaches,
Anna A. Moroz   +5 more
doaj   +1 more source

Virchow-Robin spaces : an anatomic variant or a pathologic sign? [PDF]

open access: yes, 2009
Virchow-Robin spaces surround blood vessels. Their walls are formed by prolongations of the pia mater and they have no communication with the subarachnoid space. VRS are often seen as well-delineated foci of cerebrospinal fluid signal on MR images.

core  

Impaired vasoreactivity in mildly disabled CADASIL patients [PDF]

open access: yes, 2011
Background and purpose CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) is a rare genetic disease caused by NOTCH3 gene mutations.
Campolo, J.   +16 more
core   +1 more source

Comparison of brain magnetic resonance imaging between myotonic dystrophy type 1 and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.

open access: yesPLoS ONE, 2018
BackgroundAnterior temporal lobe hyperintensities detected by brain MRI are a recognized imaging hallmark of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Hyunjin Kim   +4 more
doaj   +1 more source

Lack of effect of pravastatin on cerebral blood flow or parenchymal volume loss in elderly at risk for vascular disease [PDF]

open access: yes, 2005
<p><b>Background and Purpose:</b> Ageing is associated with a decline in cerebral blood flow. Animal studies have shown that cholesterol-lowering therapy with statins might preserve cerebral blood flow (CBF).
Blauw, G.J.   +8 more
core   +1 more source

Occurrence, Risk Factors, and Prognosis of Acute Cerebral Microinfarcts in CADASIL

open access: yesAnnals of Clinical and Translational Neurology
Introduction Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic cerebral small vessel disease in adults. This study investigates the occurrence, risk factors, and prognosis of
Xuejiao Men   +11 more
doaj   +1 more source

APT-II training in CADASIL: Can a Behavioral Treatment Build Cognitive Reserve? [PDF]

open access: yes, 2010
A single-subject, multiple-baseline across behaviors study examined the effectiveness of a modified version of Attention Process Training – II (APT-II) to treat attention in an individual with a history of multiple ischemic small-vessel infarcts and a ...
Bishop, Lilli   +2 more
core  

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