Results 151 to 160 of about 136,297 (346)
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Cadaveric simulation for improving surgical training in dermatology. [PDF]
Simulation models are rapidly changing medical education, especially the training of dermatology residents. Various models are available, including cadaveric simulations.
Connolly, Deirdre +6 more
core +1 more source
Current status of wet lab and cadaveric simulation in urological training: A systematic review
Ahmed Al‐Jabir +5 more
openalex +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Should the allocation of cadaveric kidneys for transplantation be based on HLA matching? [PDF]
R. A. P. Koene
openalex +1 more source
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Purpose Despite its close anatomical relationship with the superficial medial collateral ligament (sMCL) and deep medial collateral ligament (dMCL), the primary stabilisers of the medial knee, the anterior arm of the semimembranosus (SM) tendon has been ...
Keishiro Kikuchi +6 more
doaj +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source

