Results 151 to 160 of about 136,297 (346)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Cadaveric simulation for improving surgical training in dermatology. [PDF]

open access: yes, 2018
Simulation models are rapidly changing medical education, especially the training of dermatology residents. Various models are available, including cadaveric simulations.
Connolly, Deirdre   +6 more
core   +1 more source

Current status of wet lab and cadaveric simulation in urological training: A systematic review

open access: diamond, 2020
Ahmed Al‐Jabir   +5 more
openalex   +2 more sources

Mechanical Analysis of Five Methods of Tibiotalar Arthrodesis Using Screw Fixation Technique: A Cadaveric Study

open access: diamond, 2021
Mark C. Blackney   +4 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

A tanned cadaver

open access: yesCeylon Medical Journal, 2009
P R, Ruwanpura, J, Warushahennadi
openaire   +3 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Anatomical relationship between the anterior arm of the semimembranosus tendon and the medial collateral ligament: A cadaveric study

open access: yesJournal of Experimental Orthopaedics
Purpose Despite its close anatomical relationship with the superficial medial collateral ligament (sMCL) and deep medial collateral ligament (dMCL), the primary stabilisers of the medial knee, the anterior arm of the semimembranosus (SM) tendon has been ...
Keishiro Kikuchi   +6 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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