Results 261 to 270 of about 136,297 (346)

Human Cadaver Burial Depth Affects Soil Microbial and Nutrient Status

, 2018
Mark Pawlett, R. J. Rickson, Joanna Niziolomski, Sophie Churchill, Michal Kešner   +4 more
openalex   +2 more sources

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Back to the anatomy lab: a forgotten foundation or an ongoing necessity? [PDF]

BMC Med Educ
Temi̇zsoy Korkmaz F, Çandir Gürses BN, Balci Yapalak AN, Gürses İA.   +3 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Objective selection of bone mimetic materials using impact microindentation. [PDF]

J Orthop
Budd LR, Vaidya RS, Jahani B, Nakka S, Proctor A, Burks PT, Montgomery BK, Tang SY.   +7 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Human renal transplants. II. Immunofluorescent and immunoferritin studies. [PDF]

, 1968
Andres, GA, Calder, MW, Dossetor, JB, Hsu, KC, Porter, KA, Rendall, JM, Seegal, BC, Starzl, TE   +7 more
core  

Backwards and Bilateral: An Unexpected Variation of the Palmaris Longus. [PDF]

Cureus
Apte S, Mitchell NR, Kania I, Uduma U, Afolabi AG.   +4 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The use of cyclosporine in organ transplants [PDF]

, 1984
Gordon, RD, Iwatsuki, S, Shaw, BW, Starzl, TE   +3 more
core