Results 271 to 280 of about 174,303 (342)

Ultrasound-guided Emergency Pericardiocentesis Simulation on Human Cadavers: A Scoping Review. [PDF]

West J Emerg Med
Ünlü L, Margenfeld F, Zendehdel A, Griese JA, Poilliot A, Müller-Gerbl M, Nickel CH, Dedic M.   +7 more
europepmc   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

Articles of Significant Interest in This Issue. [PDF]

Appl Environ Microbiol
europepmc   +1 more source

Challenges of access to cadavers in low- and middle-income countries (LMIC) for undergraduate medical teaching: a review and potential solutions in the form of 3D printed replicas. [PDF]

3D Print Med
McMenamin PG, Costello LF, Quayle MR, Bertram JF, Kaka A, Tefuarani N, Adams JW.   +6 more
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Minimally invasive iliosacral sentinel lymph node mapping and extirpation: A canine cadaveric study. [PDF]

Vet Surg
Griffin MA, Porter I, Buote NJ.
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

A biosynthetic thumb prosthesis. [PDF]

NPJ Biomed Innov
Bansal S, Lai GV, Belingheri M, Kashay AQ, Kim J, Tomkinson A, Herman S, Bollavaram K, Zukotynski BK, Thomas S, Jain NS, Azari KK, Wessel LE, Clites TR.   +13 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Rare Bilateral Axillary Arch With Its Novel Insertion Into the Deltoid and Unilateral Supernumerary Head of the Sternocleidomastoid Muscle in a Single Cadaver. [PDF]

Cureus
Ara H, Fakoya AO.
europepmc   +1 more source