Results 231 to 240 of about 321,674 (333)

Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF‐κB and TGF‐β Signaling Pathways

Advanced Science, EarlyView.
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye, Jianfeng Xiang, Siqi Zhou, Qintao Ge, Aihetaimujiang Anwaier, Kun Chang, Gang Wei, Jiahe Lu, Xi Tian, Shuxuan Zhu, Yuchen Jiang, Wei Zhang, Tingting Cai, Moran Xu, Dingwei Ye, Danfeng Xu, Tao Wang, Hailiang Zhang, Wenhao Xu   +18 more
wiley   +1 more source

β-catenin condensation facilitates clustering of the cadherin/catenin complex and formation of nascent cell-cell junctions. [PDF]

Nat Commun
Monster JL, Manzato C, van der Beek JA, Pannekoek WJ, Hummelink JA, Hadders MA, de Heus C, Klumperman J, Schuijers J, Gloerich M.   +9 more
europepmc   +1 more source

Role of E-Cadherin in Membrane-Cortex Interaction Probed by Nanotube Extrusion [PDF]

, 2009
Erdem D. Tabdanov, Nicolas Borghi, Françoise Brochard‐Wyart, Sylvie Dufour, Jean Paul Thiery   +4 more
openalex   +1 more source

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

Advanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang, Zhen Wang, Shuang Li, Chao Luo, Han Li, Shengjie Ma, Pai Wang, Heshi Liu, Lijun Sun, Yue Yin, Weizhen Zhang, Quan Wang   +11 more
wiley   +1 more source

Epidermal growth factor receptor is an essential component in E-cadherin force transduction complexes. [PDF]

J Cell Sci
Zou Y, Allen N, Rauf E, Leckband D.
europepmc   +1 more source

Purification of a 92-kDa cytoplasmic protein tightly associated with the cell-cell adhesion molecule E-cadherin (uvomorulin)

, 1991
Pierre D. McCrea, Barry M. Gumbiner
openalex   +1 more source

Platelet‐activating factor increases mucosal permeability in rat intestine via tyrosine phosphorylation of E‐cadherin [PDF]

, 2000
Xiao‐Di Tan, Hong Chang, Xiao‐Wu Qu, Michael S. Caplan, Frank González-Crussí, Wei Hsueh   +5 more
openalex   +1 more source

m1A‐Dependent TRMT6/61A‐ARG2 Axis Drives Protumorigenic Senescence by Remodeling the Tumor Microenvironment

Advanced Science, EarlyView.
Uncovering a new layer of translational control, this study reveals how TRMT6/TRMT61A‐mediated tRNA‐m1A methylation drives pro‐tumorigenic senescence in colorectal cancer. By selectively enhancing ARG2 translation, this epitranscriptomic axis triggers an NF‐κB‐dependent SASP.
Tuoyang Li, Mingzhe Huang, Jinlin Cai, Xuan Li, Yaokang Xing, Rongzhao He, Zixiao Wan, Yingguo Gan, Ziming Li, Jingrong Weng, Yumo Xie, Yuanhui Wu, Xiaoxia Liu, Xiaolin Wang, Yanxin Luo, Meijin Huang, Jinxin Lin, Huichuan Yu   +17 more
wiley   +1 more source

Hydatidiform Moles: The Contribution of Ancillary Techniques in Refining Their Histopathological Diagnosis. [PDF]

Int J Mol Sci
Balan TA, Balan RA, Amalinei C, Giușcă SE, Căruntu ID.   +4 more
europepmc   +1 more source

Modulation of β-Catenin and E-Cadherin Interaction by Vpu Increases Human Immunodeficiency Virus Type 1 Particle Release [PDF]

, 2008
Aneeza Salim, Lee Ratner
openalex   +1 more source