MiR-27a-5p deficiency in plasma exosomes derived from obese individuals exacerbates ventilator-induced lung injury in vitro and in vivo. [PDF]
Wang B +8 more
europepmc +1 more source
Navigating adverse immunostimulation: A practical guide for clinical researchers
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort +3 more
wiley +1 more source
Correction to "Dexmedetomidine Attenuates Oxidative Stress Induced Lung Alveolar Epithelial Cell Apoptosis <i>In Vitro</i>". [PDF]
europepmc +1 more source
E-cadherin expression and tumor-stroma ratio as prognostic biomarkers of peritoneal recurrence in advanced gastric cancer: a digital image analysis-based stratification study. [PDF]
Lee S, Kim B.
europepmc +1 more source
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen +7 more
wiley +1 more source
The adipose tissue has an apical-basal polarity required for Col IV-dependent cell-cell adhesion. [PDF]
Almasoud J, Andrieu C, Lee BH, Franz A.
europepmc +1 more source
New opportunities for bioscaffold‐enabled spinal cord injury repair
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi +11 more
wiley +1 more source
SS18::SSX and BRD9 Modulate Synovial Sarcoma Differentiation. [PDF]
Kuntze A +10 more
europepmc +1 more source

