Results 111 to 120 of about 121,076 (308)

Binucleation ramps up gene expression meeting the physiological demands of an organism

PLoS Biology, 2022
In this issue of PLOS Biology, van Rijnberk and colleagues show how polyploidy, via binucleation, enables Caenorhabditis elegans intestinal cells to ramp up gene expression supplying the oocytes with the necessary lipids for optimal organismal growth and
Ari S. Dehn, Vicki P. Losick
doaj  

Nematophagous fungus Arthrobotrys oligospora mimics olfactory cues of sex and food to lure its nematode prey

eLife, 2017
To study the molecular basis for predator-prey coevolution, we investigated how Caenorhabditis elegans responds to the predatory fungus Arthrobotrys oligospora. C. elegans and other nematodes were attracted to volatile compounds produced by A. oligospora.
Yen-Ping Hsueh, Matthew R Gronquist, Erich M Schwarz, Ravi David Nath, Ching-Han Lee, Shalha Gharib, Frank C Schroeder, Paul W Sternberg   +7 more
doaj   +1 more source

Building phenotypic character matrices for phylogenetic inference: exploration of 35 years of practice

Biological Reviews, EarlyView.
ABSTRACT Recent methodological development in phylogenetic inference has focused predominantly on molecular data. However, renewed interest in other data types, particularly morphological data, has followed from the increased recognition of the power of total evidence and tip‐dating approaches, including fossil data, for inference of time‐scaled trees ...
Melanie J. Hopkins, Mark C. Nikolic, James D. Holmes, Daniela S. Monti, Ernesto E. Vargas‐Parra, Russell D.C. Bicknell, Gregory D. Edgecombe, Katherine Jordan‐Burmeister, John R. Paterson, Shravya Srivastava‐Losey   +9 more
wiley   +1 more source

Prereplication complex proteins get caught moonlighting

PLoS Biology, 2022
In this issue of PLOS Biology, Lattmann and colleagues report a new function for proteins of the DNA prereplication complex promoting the anchor cell to invade through the basement membrane and initiate vulval development in Caenorhabditis elegans.
Hilary A. Coller
doaj  

Evidence for adaptive explanations of semelparity in animals

Biological Reviews, EarlyView.
ABSTRACT Semelparity, the reproductive strategy of reproducing once, is widespread but uncommon in animals. Classes of models to explain the evolution of semelparity are based either on age structure and mortality schedules – demographic models in which high post‐reproductive mortality risk favours high reproductive effort and semelparity results from ...
Diana O. Fisher, Roberto Salguero‐Gómez   +1 more
wiley   +1 more source

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

Cytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

A proteomic analysis of lipid raft and GPI anchored proteins in Caenorhabditis elegans [PDF]

, 2010
Glycosylphosphatidylinositol (GPI) anchored proteins are a unique group of membrane proteins found on the surface and certain intracellular compartments of eukaryotic cells.
Rao, Wei
core  

Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1

Cytoskeleton, EarlyView.
ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley   +1 more source

The actions of chloride channel blockers, barbiturates and a benzodiazepine on Caenorhabditis elegans glutamate- and ivermectin-gated chloride channel subunits expressed in Xenopus oocytes [PDF]

, 2009
The pharmacology of Caenorhabditis elegans glutamate-gated chloride (GluCl) channels was determined by making intracellular voltage-clamp recordings from Xenopus oocytes expressing GluCl subunits. As previously reported (Cully et al.
Bush, Elizabeth, Holden-Dye, Lindy, Foreman, Richard, Walker, Robert J.   +3 more
core   +1 more source

Progress in Caenorhabditis elegans as a Degenerative Disease Model for Molecular Pathways Studying

Shiyan dongwu yu bijiao yixue
With the acceleration of population aging in China, the number of patients with degenerative diseases has exceeded ten million, urgently requiring efficient mechanism research and drug screening systems.
SUN Han, GUO Peng, YU Xinhe, ZHANG Junqiao, YAO Ying, YANG Wen   +5 more
doaj   +1 more source