Results 11 to 20 of about 121,076 (308)
A broad mutational target explains a fast rate of phenotypic evolution
eLife, 2020 The rapid evolution of a trait in a clade of organisms can be explained by the sustained action of natural selection or by a high mutational variance, that is the propensity to change under spontaneous mutation.
Fabrice Besnard +3 more
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The genome of Caenorhabditis bovis [PDF]
Current Biology, 2019 Abstract The free-living nematode Caenorhabditis elegans is a key laboratory model for metazoan biology. C. elegans is also used as a model for parasitic nematodes despite being only distantly related to most parasitic species. All ∼65
Stevens, Lewis +11 more
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Evolution of susceptibility to ingested double-stranded RNAs in Caenorhabditis nematodes. [PDF]
PLoS ONE, 2012 BACKGROUND: The nematode Caenorhabditis elegans is able to take up external double-stranded RNAs (dsRNAs) and mount an RNA interference response, leading to the inactivation of specific gene expression. The uptake of ingested dsRNAs into intestinal cells
Isabelle Nuez, Marie-Anne Félix
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Phenotypic covariance of longevity, immunity and stress resistance in the caenorhabditis nematodes. [PDF]
PLoS ONE, 2010 Ageing, immunity and stresstolerance are inherent characteristics of all organisms. In animals, these traits are regulated, at least in part, by forkhead transcription factors in response to upstream signals from the Insulin/Insulin-like growth factor ...
Francis R G Amrit +2 more
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The genome of Caenorhabditis elegans. [PDF]
Proceedings of the National Academy of Sciences, 1995 The physical map of the 100-Mb Caenorhabditis elegans genome consists of 17,500 cosmids and 3500 yeast artificial chromosomes (YACs). A total of 22.5 Mb has been sequenced, with the remainder expected by 1998. A further 15.5 Mb of unfinished sequence is freely available online: because the areas sequenced so far are relatively gene rich, about half the
Waterston, R., Sulston, J.
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BMC Genomics, 2021 Background F-box proteins represent a diverse class of adaptor proteins of the ubiquitin-proteasome system (UPS) that play critical roles in the cell cycle, signal transduction, and immune response by removing or modifying cellular regulators.
Ailan Wang, Wei Chen, Shiheng Tao
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Caenorhabditis nematodes colonize ephemeral resource patches in neotropical forests
Ecology and Evolution, 2022 Factors shaping the distribution and abundance of species include life‐history traits, population structure, and stochastic colonization–extinction dynamics. Field studies of model species groups help reveal the roles of these factors.
Solomon A. Sloat +14 more
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Oogenesis in Caenorhabditis elegans
Sexual Development, 2023 Background: The nematode, Caenorhabditis elegans has proven itself as a valuable model for investigating metazoan biology. C. elegans have a transparent body, an invariant cell lineage, and a high level of genetic conservation which makes it a desirable model organism.
Davis, Gregory M. +2 more
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American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023 Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei +4 more
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Proteomics in Caenorhabditis elegans [PDF]
Briefings in Functional Genomics and Proteomics, 2008 Proteomic approaches are increasingly being used to complement genetic and RNA interference-based studies of gene function in Caenorhabditis elegans. Several strategies to isolate protein complexes from whole worms and individual differentiated cell types have been described.
Anjon, Audhya, Arshad, Desai
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