Results 71 to 80 of about 121,076 (308)

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

A Genome-Wide RNAi Screen for Factors Involved in Neuronal Specification in Caenorhabditis elegans.

, 2011
One of the central goals of developmental neurobiology is to describe and understand the multi-tiered molecular events that control the progression of a fertilized egg to a terminally differentiated neuron.
Poole Richard J., Eileen B. Flowers, Bashllari Enkelejda, Flowers Eileen B., Cochella, L, Oliver Hobert, Hobert Oliver, Flowers, EB, Luisa Cochella, Cochella Luisa, Bashllari, E, Hobert, O, Eileen B Flowers, Enkelejda Bashllari, Poole, RJ, Richard J Poole, Richard J. Poole   +16 more
core   +1 more source

Evaluating the power and limitations of genome-wide association studies in Caenorhabditis elegans

G3: Genes, Genomes, Genetics, 2022
Quantitative genetics in Caenorhabditis elegansC. elegansC. elegansC. elegansC.
Samuel J Widmayer, Kathryn S Evans, Stefan Zdraljevic, Erik C Andersen   +3 more
doaj   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

Advanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha, Linda Kloss, Juan D. Montenegro, Simone Albani, Audrey Ortega‐Ramírez, Mihaela Raycheva, Sylvia Joussen, Sabrina Kaul, Michèle Bachmann, Lisa Huf, Günther Schmalzing, Alison G. Cole, Ulrich Technau, Stefan Gründer   +13 more
wiley   +1 more source

Annotation of two large contiguous regions from the Haemonchus contortus genome using RNA-seq and comparative analysis with Caenorhabditis elegans [PDF]

, 2011
The genomes of numerous parasitic nematodes are currently being sequenced, but their complexity and size, together with high levels of intra-specific sequence variation and a lack of reference genomes, makes their assembly and annotation a challenging ...
Gilleard John S., Protasio Anna V., Anna V Protasio, Laing Roz, Jackson Frank, Hunt, M., Steven Laing, Beech, R., Laing, S., Frank Jackson, Mungall, K., Michael Quail, Saunders Gary, Hunt Martin, Gilleard, J.S., Quail Michael, Mungall Karen, Berriman, M., Gary Saunders, Anna V. Protasio, Laing Steven, Beech Robin, Martin Hunt, Robin Beech, Saunders, G., Jackson, F., Karen Mungall, Quail, M., Matthew Berriman, Roz Laing, Laing, R., John S Gilleard, John S. Gilleard, Protasio, A.V., Berriman Matthew   +34 more
core   +1 more source

Drop‐Shaped Optical Microfiber Enabled Biomechanical Sensor

Advanced Science, EarlyView.
A novel microforce sensor based on a drop‐shaped optical microfiber is presented herein, designed to characterize the biomechanical properties of single cells and microscale living organisms, achieving a force resolution of 24 nN. Leveraging its high sensitivity, facile miniaturization, excellent flexibility, and robust mechanical stability, this ...
Yan Xu, Xitao Tu, Haochen Jiang, Jun Mo, Xinyue Zhang, Xiaomin Yue, Limin Tong, Lei Zhang   +7 more
wiley   +1 more source

Identification and characterization of agrin in "Caenorhabditis elegans" [PDF]

, 2006
Agrin is a large basement membrane (BM) proteoglycan expressed in many tissues in vertebrates, with particularly important function at the neuromuscular junction (NMJ) where it clusters acetylcholine receptors (AChRs) and maintains structural stability ...
Hrus, Ana
core   +1 more source

Comparative genomics of 10 new Caenorhabditis species

Evolution Letters, 2019
The nematode Caenorhabditis elegans has been central to the understanding of metazoan biology. However, C. elegans is but one species among millions and the significance of this important model organism will only be fully revealed if it is placed in a ...
Lewis Stevens, Marie‐Anne Félix, Toni Beltran, Christian Braendle, Carlos Caurcel, Sarah Fausett, David Fitch, Lise Frézal, Charlie Gosse, Taniya Kaur, Karin Kiontke, Matthew D. Newton, Luke M. Noble, Aurélien Richaud, Matthew V. Rockman, Walter Sudhaus, Mark Blaxter   +16 more
doaj   +1 more source

Subcellular patterns of SPE-6 localization reveal unexpected complexities in Caenorhabditis elegans sperm activation and sperm function

G3: Genes, Genomes, Genetics, 2021
To acquire and maintain directed cell motility, Caenorhabditis elegansC.
Jackson J Peterson, Claire E Tocheny, Gaurav Prajapati, Craig W LaMunyon, Diane C Shakes   +4 more
doaj   +1 more source

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

Advanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu, Shiming Zhu, Sishi Xia, Xiaoshuai Zhang, Qin Li, Zhanquan Zeng, Yuqing Liu, Wanyin Liang, Guanyu Zhou, Erxia Du, Suning Liu, Sheng Li   +11 more
wiley   +1 more source